Researchers with an interest in unraveling gene regulation in human health and disease are expanding their horizons by closely looking at alternative polyadenylation (APA), an under-charted mechanism that regulates gene expression.
Other
Jul 23, 2020
0
4
Growth and development of all organisms depends on coordinated regulation of gene expression in time and space, and this is largely controlled by non-coding sequences in the genome. A major challenge in genomics-enabled crop ...
Plants & Animals
Jul 7, 2020
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1
Deserts of the U.S. Southwest are extreme habitats for most plants, but, remarkably, microscopic green algae live there that are extraordinarily tolerant of dehydration. These tiny green algae (many just a few microns in ...
Plants & Animals
Jul 6, 2020
0
37
All life depends on a genome, which acts as an instruction manual for building all the products essential for development and survival. But knowing which of these individual instructions—or genes—need to be read, and ...
Cell & Microbiology
Jun 30, 2020
0
9
New images of an enzyme in action as it interacts with the chromosome could provide important insight into how cells—including cancer cells—regulate their genes.
Molecular & Computational biology
Jun 4, 2020
0
113
While the first genome-wide DNA methylation map in mammalian cells was established over 10 years ago, such maps only provide snapshots and do not inform about the actual dynamics of this epigenetic mark. Researchers from ...
Biotechnology
Jun 2, 2020
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16
Bacteria have a cunning ability to survive in unfriendly environments.
Molecular & Computational biology
May 29, 2020
0
152
The discovery of a huge number of long non-protein coding RNAs, aka lncRNAs, in the mammalian genome was a major surprise of the recent large-scale genomics projects. An international team including a bioinformatician from ...
Biotechnology
May 15, 2020
0
252
A cell is a complex machine whose flexible architecture enables it to take part in life's activities: relaying information, managing waste, responding to stress.
Cell & Microbiology
Apr 27, 2020
0
4
Until recently, little was known about how transposable elements contribute to gene regulation. These are little pieces of DNA that can replicate themselves and spread out in the genome. Although they make up nearly half ...
Biotechnology
Apr 15, 2020
0
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