In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring ...
Molecular & Computational biology
Jan 12, 2023
0
24
The initiation of the innate immune responses relies on the detection of microbes by multiple pattern recognition receptors. Among these receptors, cyclic GMP-AMP synthase (cGAS) has been identified as a major and universal ...
Cell & Microbiology
Sep 8, 2022
0
4
New collaborative research from Northwestern University and Lund University may have people heading to their backyard instead of the store at the outset of this year's mosquito season.
Plants & Animals
Mar 4, 2021
1
327
For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals. Critical for brain ...
Cell & Microbiology
Jun 30, 2020
0
265
For researchers looking to understand and someday treat certain neuropsychological ailments, one place to start is a molecule known as GABA, which binds to receptor molecules in neurons and helps regulate neuron firing rates ...
Molecular & Computational biology
Jun 17, 2020
0
177
EPFL scientists have developed a computational method modeling and designing protein allostery that allows the accurate and rational engineering and even repurposing of cell receptors. The method can be a significant tool ...
Biochemistry
Dec 2, 2019
0
36
Antonella Di Pizio and Maik Behrens of the Leibniz-Institute for Food Systems Biology at the Technical University of Munich, together with their cooperation partners, have developed highly effective activators for the bitter ...
Biochemistry
Jul 1, 2019
0
0
It might be one of nature's most agile and calculating hunters, but the wolf spider won't harm an insect that literally leaves a bad taste in its mouth, according to new research by a team of Wake Forest University sensory ...
Plants & Animals
Apr 15, 2019
0
22
The human nose can distinguish one trillion different scents—an extraordinary feat that requires 10 million specialized nerve cells, or neurons, in the nose, and a family of more than 400 dedicated genes. But precisely ...
Biotechnology
Jan 9, 2019
1
53
If certain signaling cascades are misregulated, diseases like cancer, obesity and diabetes may occur. A mechanism recently discovered by scientists at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in ...
Cell & Microbiology
Aug 15, 2018
0
2
