A new tool to predict the chances of successfully inserting a gene-edited sequence of DNA into the genome of a cell, using a technique known as prime editing, has been developed by researchers at the Wellcome Sanger Institute. ...
Biotechnology
Feb 16, 2023
0
17
A lethal microbial pathogen is lurking in warm freshwater ponds, reservoirs, and rivers around the globe: Naegleria fowleri, colloquially called brain-eating amoeba, which causes the disease primary amebic meningoencephalitis ...
Biochemistry
Feb 9, 2023
0
8
Researchers at the UAB have determined the structure of amyloid fibers formed by the protein hnRNPDL-2, implicated in limb-girdle muscular dystrophy type 3, using high-resolution cryo-electron microscopy (cryo-EM). They have ...
Biotechnology
Feb 3, 2023
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68
Medical innovations typically take 17 years from the time a lightbulb goes off in a scientist's head until the first person benefits.
Biotechnology
Jan 31, 2023
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18
Over the past 10 years, CRISPR has been transformative for research, enabling gene editing that is fast, simple and precise, experts say.
Biotechnology
Jan 31, 2023
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20
An international research group has for the first time reconstructed ancestors dating back 2.6 billion years of the well-known CRISPR-Cas system, and studied their evolution over time. The results suggest that the revitalized ...
Cell & Microbiology
Jan 4, 2023
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1254
Investigators have identified a novel role for an intracellular trafficking pathway in regulating epidermal developmental processes, which could serve as a future therapeutic target for inflammatory skin diseases, according ...
Cell & Microbiology
Dec 12, 2022
0
14
Ribosomes, the tiny protein-producing factories within cells, are ubiquitous and look largely identical across the tree of life. Those that keep bacteria chugging along are, structurally, not much different from the ribosomes ...
Cell & Microbiology
Dec 8, 2022
0
18
Scientists have shown that in one in every 4,000 births, some of the genetic code from our mitochondria—the 'batteries' that power our cells—inserts itself into our DNA, revealing a surprising new insight into how humans ...
Molecular & Computational biology
Oct 5, 2022
0
447
Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...
Molecular & Computational biology
Aug 5, 2022
0
80
