News tagged with rapamycin
Longevity pill on the horizon?
(PhysOrg.com) -- While applauding findings that an Easter Island compound extends the lives of middle-aged mice, University of Washington longevity researchers caution that healthy people shouldn't start taking the drug in ...
Medicine & Health / Medical research
Jul 10, 2009 |
4.4 / 5 (17) |
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Discovery may aid search for anti-aging drugs
A team of University of Michigan scientists has found that suppressing a newly discovered gene lengthens the lifespan of roundworms. Scientists who study aging have long known that significantly restricting food intake makes ...
Aug 18, 2010 |
5 / 5 (11) |
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A drug that extends life span prevents Alzheimer's deficits
If research results continue to be repeated and are turned into clinical trials, a drug already approved for some uses could be marshaled -- sooner than we expect -- to prevent Alzheimer's disease in humans and improve health ...
Medicine & Health / Medical research
Apr 01, 2010 |
5 / 5 (10) |
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Perhaps a longer lifespan, certainly a longer 'health span'
Organisms from yeast to rodents to humans all benefit from cutting calories. In less complex organisms, restricting calories can double or even triple lifespan. It's not yet clear just how much longer calorie restriction ...
Medicine & Health / Medical research
Apr 15, 2010 |
4.6 / 5 (10) |
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Red wine compound increases anti-tumor effect of rapamycin
Cleveland – Researchers from Cleveland Clinic's Lerner Research Institute have discovered that resveratrol – a compound found in red wine – when combined with rapamycin can have a tumor-suppressing effect on ...
Feb 14, 2011 |
4.5 / 5 (8) |
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Grapefruit juice boosts drug's anti-cancer effects
In a small, early clinical trial, researchers at the University of Chicago Medical Center have found that combining eight ounces of grapefruit juice with the drug rapamycin can increase drug levels, allowing lower doses of ...
Apr 20, 2009 |
4.6 / 5 (7) |
1
Cancer-causing gene discovery suggests new therapies
Scientists have discovered a novel way by which a much-studied cancer-promoting gene accelerates the disease. The finding suggests a new strategy to halt cancer's progress.
Jan 24, 2009 |
5 / 5 (6) |
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Research discovery may lead to advances in heart disease and cancer treatment
Research led by T. Cooper Woods, PhD, Assistant Professor of Pharmacology and Experimental Therapeutics at LSU Health Sciences Center New Orleans, and Director of the Molecular Cardiology Research Laboratory at Ochsner Clinic ...
Apr 14, 2010 |
5 / 5 (1) |
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Sirolimus
Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. A macrolide, sirolimus was first discovered as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island — an island also known as "Rapa Nui", hence the name. It is marketed under the trade name Rapamune by Wyeth.
Sirolimus was originally developed as an antifungal agent. However, this was abandoned when it was discovered that it had potent immunosuppressive and antiproliferative properties.
For more information about Sirolimus, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
