How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details of mutation-induced subtle ...
Biochemistry
Apr 16, 2024
0
0
A recent UCLA study demonstrates a new process for screening T cells, part of the body's natural defenses, for characteristics vital to the success of cell-based treatments. The method filters T cells based on the receptor ...
Bio & Medicine
Apr 15, 2024
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46
A new study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions.
Cell & Microbiology
Apr 12, 2024
0
68
In cellular biology, unraveling the complexities of cellular function at the molecular level remains a paramount endeavor. Significant scientific focus has been placed on understanding the interactions at organelle contact ...
Cell & Microbiology
Apr 12, 2024
0
32
Imagine tuning into a football game, but all of the players are invisible except for the two quarterbacks. Without being able to see the orchestrated movements of the full teams, this would be a very confusing game to watch.
Cell & Microbiology
Apr 11, 2024
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65
Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells.
Biochemistry
Apr 11, 2024
0
34
As a scientist, lab work can sometimes get monotonous. But in 2017, while a Ph.D. student of paleobiology at the University of Bristol in the U.K., I heard a gleeful exclamation from across the room. Kirsty Penkman, head ...
Paleontology & Fossils
Apr 10, 2024
0
965
Cells contain various specialized structures—such as the nucleus, mitochondria or peroxisomes—known as "organelles." Tracing their genesis and determining their structure is fundamental to understanding cell function ...
Cell & Microbiology
Apr 10, 2024
0
124
Scientists have successfully used a new imaging technique to determine the structure and interactions of a protein complex that plays a significant part in the initiation and progression of cancer. They showed that it was ...
Biotechnology
Apr 10, 2024
0
10
Cats communicate with others through their scents. One of their scent-marking behaviors is spraying urine on vertical surfaces such as walls and furniture. Although spraying plays an essential role in the feline world, it ...
Biochemistry
Apr 10, 2024
0
64
