Thousands of proteins undergo arginine N-methylation, a widespread post-translational modification catalyzed by several protein arginine methyltransferases (PRMTs) that covalently link methyl groups to arginine side chains. ...
Biotechnology
Jul 19, 2021
0
6
A research group working at Uppsala University has succeeded in studying 'translation factors' – important components of a cell's protein synthesis machinery—that are several billion years old. By studying these ancient ...
Molecular & Computational biology
Apr 29, 2021
0
42
Trypanosomatids are single-cell parasites that cause major diseases, such as sleeping sickness and Rose of Jericho, which affect millions of people. Trypanosoma parasites are transmitted to mammals by the blood-sucking tsetse ...
Cell & Microbiology
Mar 17, 2021
0
43
On Feb 5th, Seoul National University, College of Engineering (Dean Kookheon Char) announced that Professor Sang Woo Seo's research team (Dr. Jina Yang and Mr. Yong Hee Han) at the School of Chemical and Biological Engineering ...
Biochemistry
Feb 8, 2021
0
80
Just like people, cells get stressed too. A sudden drop in oxygen, overheating, or toxins can trigger a cascade of molecular changes that lead cells to stop growing, produce stress-protective factors, and form stress granules—proteins ...
Cell & Microbiology
Dec 14, 2020
0
19
Since mRNAs play a key role in protein synthesis in vivo, the use of mRNAs as medicines and for in vitro protein synthesis has been desired. In particular, mRNA therapeutics hold the potential for application to vaccine therapy ...
Molecular & Computational biology
Jul 16, 2020
0
59
Skoltech scientists and their colleagues have studied more than 30 thousand variants of genetic sequences encoding two fluorescent proteins in order to determine which characteristics of mRNA and of the first dozen or so ...
Molecular & Computational biology
May 28, 2020
0
4
Humans are living longer than ever before. But alongside these increases in life expectancy are an increase in the occurrence of age-related diseases such as cancer and dementia.
Molecular & Computational biology
May 20, 2020
1
168
The instructions of life encoded in our genes are decoded through the translation into mRNA, which then instructs the synthesis of proteins. Because mRNA translation is an essential process, it is carefully coordinated through ...
Biotechnology
Feb 28, 2020
0
4
Defects in tRNA biogenesis influence gene expression and are associated with many types of human diseases, such as cancer and neurological diseases. In his thesis, Fu Xu contributes to new knowledge about the factors that ...
Molecular & Computational biology
Jan 16, 2020
0
4
