First mouse model with mitochondrial tRNALeu mutation developed

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial ...

Newly identified compound binds to Shiga toxin to reduce its toxicity

A strain of E. coli bacteria called enterohemorrhagic E. coli (EHEC) is known to cause several gastrointestinal disorders, which include bloody diarrhea and abdominal cramps, by damaging the intestinal lining. When accompanied ...

Taste sensors keep proteins in order in flies

A set of genes that promote sweet taste sensation is also crucial for protein management during fly development, according to a new study by Eugenia Piddini of the University of Bristol, United Kingdom, and colleagues, publishing ...

Study describes new way of generating insulin-producing cells

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for ...

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