Producing protein from circular RNA in E.Coli
Circular RNAs were recently shown to be abundant in mice and humans where they influence gene expression.
Circular RNAs were recently shown to be abundant in mice and humans where they influence gene expression.
Many genes are transcribed into messenger RNA (mRNA) molecules that provide instructions for protein synthesis. Other genes encode regulatory RNAs known as 'microRNAs', which can block protein translation ...
How does the bacterium Shigella—the cause of a deadly diarrheal disease—detect that it's in a human host? Ohio University scientists have found that a biological "RNA thermometer" monitors whether the environment is rig ...
(Phys.org) —BBSRC-funded researchers have developed a new strategy that can give scientists a better insight into how complex molecular machineries function in living cells.
Biochemists at the University of Massachusetts Amherst including assistant professor Peter Chien recently gained new insight into how protein synthesis and degradation help to regulate the delicate ballet ...
Studied for decades for their essential role in making proteins within cells, several amino acids known as tRNA synthetases were recently found to have an unexpected – and critical – additional role in cancer metastasis ...
A research team in Japan exploring the functions of messenger ribonucleic acid (mRNA) – a molecule that encodes the chemical blueprint for protein synthesis – has discovered a way to take a close look at the temperature ...
(Phys.org)—Multiple RNA sequences can code for the same amino acid, but differences in their respective "optimality" slow or accelerate protein translation. Stanford biologists find optimal and non-optimal ...
Many different tissues and organs form from pluripotent stem cells during embryonic development. To date it had been known that these processes are controlled by transcription factors for specific tissues. ...
Distillers dried grains with solubles (DDGS) are a good source of energy and protein in swine diets. However, they can be damaged by excessive heat during processing, compromising their nutritional value. University of Illinois ...
Southwest Research Institute (SwRI) has developed a unique software program that enables prescreening of the three-dimensional structure of proteins and enzymes for pharmaceutical and biochemical research ...
(Phys.org)—Cells experience stress in multiple ways. Temperature shifts, mis-folded proteins and oxidative damage can all cause cellular stress. But whatever the form of the stress, all cells quickly stop ...
At crucial points in the metabolism of all organisms, a protein with the unwieldy name of Translation Elongation Factor P (EF-P, for short) takes center stage. What it actually does during protein synthesis has only now been ...
(Phys.org)—The nucleic acid RNA is an essential part of the critical process by which the cells in our bodies manufacture proteins. But noncoding RNAs also exist whose sequences, while not converted into ...