DNA sequencing has changed biology like nothing else since the origin of species theory. In particular, the way we investigate microbial life has fundamentally changed. Today, we are able to sequence DNA with unprecedented ...
Researchers have visualized the protein binding site of the (pro)renin receptor known to be involved in pancreatic cancer development using an artificial intelligence-based protein structure prediction program. They predicted ...
Cell & Microbiology
Dec 9, 2022
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40
Modern eukaryotic cells contain numerous organelles, which once used to be independent bacteria. In order to understand how these bacteria were integrated into the cells in the course of evolution and how they are controlled, ...
Evolution
Dec 7, 2022
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63
New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...
Biochemistry
Dec 5, 2022
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15
A defense mechanism that human cells possess against viruses such as monkeypox, herpes simplex and human papillomavirus—all double-stranded DNA viruses—relies on proteins that patrol the cell, acting as sensors of the ...
Biotechnology
Nov 29, 2022
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39
The vast majority of vertebrate species living today, including humans, belong to the jawed vertebrate group. The development of articulating jaws during vertebrate evolution was one of the most significant evolutionary transitions ...
Evolution
Nov 25, 2022
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301
Nucleobase-containing coenzymes are believed to be the relics of an ancient RNA world and can provide information on the origin and evolution of proteins. However, coenzyme-protein interactions largely remain unclear.
Biochemistry
Nov 25, 2022
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20
Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes. mRNA sequences can be designed to encode specific proteins; the ...
Bio & Medicine
Nov 10, 2022
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30
Vikas Nanda has spent more than two decades studying the intricacies of proteins, the highly complex substances present in all living organisms. The Rutgers scientist has long contemplated how the unique patterns of amino ...
Biochemistry
Nov 2, 2022
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82
Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest ...
Biotechnology
Oct 27, 2022
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