In a groundbreaking study, researchers have unveiled a previously unknown conformational state of a crucial transporter protein, OxlT, which plays a vital role in preventing kidney stone formation. This discovery, achieved ...
Biochemistry
Jan 29, 2024
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46
In a world where the intricacies of molecular biology often seem as vast and mysterious as the cosmos, a new study delves into the microscopic universe of proteins, unveiling a fascinating aspect of their existence. This ...
Molecular & Computational biology
Jan 22, 2024
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64
In a study published in Nature Biotechnology, Gao Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed a series of new prime editors based on the Cas12a ...
Biotechnology
Jan 11, 2024
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30
Knowing exactly how beef cattle utilize protein is important to answering many nutrition questions producers and industry nutritionists pose to Texas A&M AgriLife Extension Service specialists like Jason Smith, Ph.D., Amarillo.
Agriculture
Jan 11, 2024
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6
Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal ...
Cell & Microbiology
Jan 2, 2024
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66
Today, medicines based on antibodies—proteins that fight infection and disease—are prescribed for everything from cancer to COVID-19 to high cholesterol. The antibody drugs are supplied by genetically-engineered cells ...
Biotechnology
Dec 12, 2023
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74
Most diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great ...
Biochemistry
Dec 11, 2023
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57
A central component of the human immune system, the NLRP3 inflammasome plays an important role in fighting off infections. However, its chronic activation is also implicated in a variety of common diseases, such as Alzheimer's, ...
Molecular & Computational biology
Dec 8, 2023
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21
The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications ...
Molecular & Computational biology
Dec 6, 2023
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2
A team of chemists, microbiologists and physicists at the University of Cambridge in the U.K. has developed a way to use solid-state nanopores and multiplexed DNA barcoding to identify misfolded proteins such as those involved ...
