Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many ...
Biochemistry
Aug 20, 2014
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Proteins are like machines. For some diseases, it can be useful to turn these machine off or on when they are too active or not active enough. One way to control switching in a protein, such as a nuclear receptor, is to put ...
Molecular & Computational biology
Jun 1, 2022
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5
Whenever you choke on acrid cigarette smoke, feel like you're burning up from a mouthful of wasabi-laced sushi, or cry while cutting raw onions and garlic, your response is being triggered by a primordial chemical sensor ...
Biochemistry
Mar 17, 2010
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In a study published in Current Opinion in Structural Biology, MIPT biophysicists explained ways to visualize membrane receptors in their different states. Detailed information on the structure and dynamics of these proteins ...
Cell & Microbiology
May 21, 2020
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9
(Phys.org)—A research team at Weill Cornell Medical College has solved the 3D crystal structure of a member protein in one of the most important classes of human proteins—the G protein-coupled receptors (GPCRs). These ...
Cell & Microbiology
Feb 27, 2013
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Readers of the top-ranked scientific journals Science and Nature might have noticed a recent wave of articles, most recently in the July 13, 2012 issue of Science, with deep importance for biology and medicine. These papers, ...
Cell & Microbiology
Jul 12, 2012
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0
A team of plant geneticists at Cold Spring Harbor Laboratory (CSHL) has identified a protein receptor on stem cells involved in plant development that can issue different instructions about how to grow depending on what peptide ...
Biotechnology
Mar 22, 2018
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128
(Phys.org) —When plants discover a pathogen, they prepare for system-wide attack so they are ready to fight on all levels. Working with colleagues, Annegret Ross and Yusuke Saijo of the Max Planck Institute for Plant Breeding ...
Biotechnology
Dec 17, 2013
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0
Researchers have developed a light-activated tool to show how drugs need to be adapted to combat type 2 diabetes.
Biochemistry
Apr 11, 2016
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30
Researchers at the University of Michigan, Stanford University and biotech company ConfometRx have captured the first cryo-electron microscopy snapshots of a key cellular receptor in action.
Biochemistry
May 24, 2017
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