News tagged with protein p53
Scientists show TAp63 suppresses cancer metastasis
Long overshadowed by p53, its famous tumor-suppressing sibling, the p63 gene does the tougher, important job of stifling the spread of cancer to other organs, researchers at The University of Texas MD Anderson Cancer Center ...
Oct 20, 2010 |
5 / 5 (4) |
0
|
Use the common cold virus to target and disrupt cancer cells?
A novel mechanism used by adenovirus to sidestep the cell's suicide program, could go a long way to explain how tumor suppressor genes are silenced in tumor cells and pave the way for a new type of targeted ...
Aug 25, 2010 |
4.8 / 5 (5) |
0
|
Loss of Tumor-Suppressor and DNA-Maintenance Proteins Causes Tissue Demise, Study Finds
(PhysOrg.com) -- A study published in the October issue of Nature Genetics demonstrates that loss of the tumor-suppressor protein p53, coupled with elimination of the DNA-maintenance protein ATR, severely disrup ...
Oct 15, 2009 |
5 / 5 (1) |
0
Researchers identify potential molecular target to prevent growth of cancer cells
Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor. This finding by researchers at the University of ...
Sep 16, 2011 |
5 / 5 (7) |
0
|
A chaperone for the 'guardian of the genome'
The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...
Sep 07, 2011 |
5 / 5 (3) |
0
|
Computer modeling used to study protein involved with cancer, aging and chronic disease
(PhysOrg.com) -- A new biophysical and biochemical study may lead to better understanding of how structural flexibility controls the interaction of a protein that is closely involved with cancer, aging and other chronic diseases ...
Apr 13, 2011 |
not rated yet |
0
|
Protein and microRNA block cellular transition vital to metastasis
Like a bounty hunter returning escapees to custody, a cancer-fighting gene converts organ cells that change into highly mobile stem cells back to their original, stationary state, researchers report online at Nature Cell Bi ...
Feb 25, 2011 |
4.8 / 5 (4) |
0
|
Restoring the gene for cancer protein p53 slows spread of advanced tumors
(PhysOrg.com) -- In a new study to be published in the Nov. 25 issue of Nature, MIT cancer biologists show that restoring the protein p53's function in mice with lung cancer has no effect early in tumor develo ...
Nov 24, 2010 |
not rated yet |
1
|
Advances reported in quest for drugs targeting childhood cancer
Investigators believe they have identified the founding member of a chemical family they hope will lead to a new class of cancer drugs, the first designed specifically against a childhood tumor, according ...
Mar 29, 2010 |
4 / 5 (1) |
0
|
Researchers pinpoint a new enemy for tumor-suppressor p53
Researchers at The University of Texas M. D. Anderson Cancer Center have identified a protein that marks the tumor suppressor p53 for destruction, providing a potential new avenue for restoring p53 in cancer ...
Jun 26, 2009 |
4.5 / 5 (10) |
3
Toward new drugs that turn genes on and off
Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, ...
Jun 04, 2009 |
5 / 5 (6) |
0
Most common brain cancer may originate in neural stem cells
University of Michigan scientists have found that a deficiency in a key tumor suppressor gene in the brain leads to the most common type of adult brain cancer. The study, conducted in mice that mimic human cancer, points ...
Jun 01, 2009 |
5 / 5 (1) |
0
New research on the 'guardian of the genome'
(PhysOrg.com) -- Protein p53 protects the body against cancer and is knocked out in many cancer tumours. Researchers at Karolinska Institutet have identified two molecules that can restore p53's cancer-killing properties. ...
May 12, 2009 |
5 / 5 (2) |
0
Cancer is a p53 protein aggregation disease
Protein aggregation, generally associated with Alzheimer's and mad cow disease, turns out to play a significant role in cancer. In a paper published in Nature Chemical Biology, Frederic Rousseau and Joost Schymkowitz of VIB ...
Mar 29, 2011 |
not rated yet |
0
Eggs' quality control mechanism explained
To protect the health of future generations, body keeps a careful watch on its precious and limited supply of eggs. That's done through a key quality control process in oocytes (the immature eggs), which ensures elimination ...
Feb 17, 2011 |
not rated yet |
0
