Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation. Members of the Institute of Veterinary Biochemistry and Molecular Biology ...
Mar 10, 2013
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(Phys.org)— A diverse group of researchers from the U.S. and China has discovered a molecule that allows for controlling the movements of animals using only light. In their paper published in the journal Nature Chemical Bi ...
Feb 11, 2013
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(Phys.org)—Scientists from the Friedrich Miescher Institute for Biomedical Research have elucidated the histone modifications that lead to the sequestration of silent genes at the nuclear periphery. In ...
Aug 31, 2012
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It's widely accepted that molecular mechanisms mediating epigenetics include DNA methylation and histone modifications, but a team from Thomas Jefferson University has evidence to the contrary regarding the role of histone ...
Aug 23, 2012
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Transcription is a cellular process by which genetic information from DNA is copied to messenger RNA for protein production. But anticancer drugs and environmental chemicals can sometimes interrupt this flow of genetic information ...
Aug 21, 2012
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Scientists at The Scripps Research Institute have simultaneously mapped two of the most important types of protein-modification in cells, revealing their extensive cooperation during an essential cellular process.
Jul 19, 2012
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For years, science has generally considered the phosphorylation of proteins -- the insertion of a phosphorous group into a protein that turns it on or off -- as perhaps the factor regulating a range of cellular processes ...
Dec 11, 2011
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The trifecta of biological proof is to take a discovery made in a simple model organism like baker's yeast and track down its analogs or homologs in "higher" creatures right up the complexity scale to people, ...
Dec 05, 2011
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Johns Hopkins researchers report the discovery of a molecular switch that regulates the behavior of a protein that, when altered, is already known to increase human susceptibility to schizophrenia and mood disorders.
Apr 06, 2011
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Scientists have observed, for the first time, an intermediate stage in the chemical process that repairs DNA methylation damage and regulates many important biological functions that impact health conditions ...
Nov 10, 2010
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(PhysOrg.com) -- Various processes in our body are controlled by subsequent changes of proteins. Therefore, the identification of such modifications is essential for the further exploration of our organism. ...
May 27, 2010
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(PhysOrg.com) -- The growth of cancerous tumors is fueled, at least in part, by the buildup of free radicals -- highly reactive oxygen-containing molecules.
Sep 08, 2009
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A team of scientists from the University of Copenhagen and the Max Planck Institute in Germany, has identified no less than 3,600 molecular switches in the human body. These switches, which regulate protein functions, may ...
Jul 17, 2009
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In a paper publishing online April 23rd in Cell Stem Cell, a Cell Press journal, Dr. Sheng Ding and colleagues from the Scripps Research Institute in La Jolla, California, report an important step forward in the race to mak ...
Apr 23, 2009
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A new study identifies a protein that modifies the androgen receptor (AR) and influences its ability to regulate target genes linked with the progression of prostate cancer. The research, published by Cell Press in the April ...
Apr 06, 2009
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