Review: PROTACs targeting epigenetic proteins

The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications ...

How chemical modifications on DNA keep genes silent

Several diseases, including certain types of cancer and some neurodevelopmental conditions, have aberrant patterns of DNA methylation, a chemical modification that regulates gene expression in ways that keep genes in the ...

Using nanopores to detect epigenetic changes faster

Changes known as epigenetic modifications play an important role in cancer development. Being able to analyze them quickly and reliably could contribute significantly to the further development of personalized therapy. A ...

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