An effort to develop software that unravels the complexities of how proteins fold is paying dividends in new findings on how they misfold, according to researchers at Rice University.
Jan 14, 2013
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(Phys.org) -- Researchers at the University of Alberta's physics department and the National Institute for Nanotechnology (NINT) are the first to map out the folding pathways of prions, malformed ...
May 30, 2012
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(Phys.org) -- University of Delaware assistant professor David W. Colby is co-author of a paper in the March 23 issue of the Journal of Biological Chemistry that suggests protein misfolding may occur early in th ...
Apr 06, 2012
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Two related studies from Northwestern University offer new strategies for tackling the challenges of preventing and treating diseases of protein folding, such as Alzheimer's, Parkinson's and Huntington's diseases, amyotrophic ...
Jan 06, 2012
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Vijay Pande's chemistry and structural biology group at Stanford has become known for Folding@home, a distributed computing project that borrows computing time from home computers to simulate how proteins take ...
Nov 21, 2011
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(PhysOrg.com) -- Troubled proteins in need of rescue may someday have a champion in a common drug used to treat high blood pressure.
Jun 24, 2011
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Scientists from the Florida campus of The Scripps Research Institute have uncovered a potentially important new therapeutic target that could prevent stress-related cell death, a characteristic of neurodegenerative diseases ...
Jun 02, 2011
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A large number of illnesses stem from misfolded proteins, molecules composed of amino acids. Researchers at the University of Zurich have now studied protein misfolding using a special spectroscopic technique. ...
May 31, 2011
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University of Michigan scientists have identified events inside insulin-producing pancreatic cells that set the stage for a neonatal form of non-autoimmune type 1 diabetes, and may play a role in type 2 diabetes as well. ...
Oct 12, 2010
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(PhysOrg.com) -- All proteins self-assemble in a fraction of the blink of an eye, but it can take a long time to mimic the process. And there has been no guarantee of success, even with the most powerful computers - until ...
Jul 06, 2010
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Light chain amyloidosis, a deadly protein misfolding disease, is caused by multiple mutations in cells that are intended to protect the body. Instead, the mutations send misfolded bundles of proteins through the bloodstream, ...
May 11, 2010
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In findings that advance scientists' understanding of a whole class of inherited disorders, a team from The Scripps Research Institute has shed light on a mechanism that enables a potential treatment for Gaucher's disease ...
May 09, 2010
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Scientists at Duke University Medical Center have found some compounds that improve a cell's ability to properly "fold" proteins and could lead to promising drugs for degenerative nerve diseases, including Huntington's disease, ...
Jan 19, 2010
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(PhysOrg.com) -- Like yoga for office drones, cells do have coping strategies for stress. Heat, lack of nutrients, oxygen radicals - all can wreak havoc on the delicate internal components of a cell, potentially ...
Oct 29, 2009
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Scientists from Texas are batty over a new discovery which could lead to the single most important medical breakthrough in human history -- significantly longer lifespans. The discovery, featured on the cover of the July ...
Jun 30, 2009
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