Cellular stress, or oxidative stress, occurs when there is a buildup of reactive oxygen species (ROS), which interferes with cellular mechanisms and can even cause damage to proteins, lipids, and DNA. Due to their destructive ...
Cell & Microbiology
Jun 12, 2023
0
17
A screening technique commonly used in drug discovery can yield important details about the actions of molecular 'glues' in protein interactions.
Biochemistry
Jun 8, 2023
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8
A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.
Cell & Microbiology
May 16, 2023
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100
Proteins are the key players for virtually all molecular processes within the cell. To fulfill their diverse functions, they have to interact with other proteins. Such protein-protein interactions are mediated by highly complementary ...
Evolution
Apr 6, 2023
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66
The Allain (IBC), Gossert (BNSP) and Leitner (IMSB) groups investigated the druggability of the SARS-CoV-2 Nucleocapsid protein RNA interactions by a hybrid structure determination approach, which led to the identification ...
Molecular & Computational biology
Apr 3, 2023
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1
A research group of 46, led by the University of Utah School of Medicine, reports an innovative new method to analyze 33 enzymes from human carbohydrate metabolism and identify 830 protein-metabolite interactions, including ...
St. Jude Children's Research Hospital scientists solved the 3D structure of a major protein complex in cilia, signaling appendages found on cells. The structure was captured at the highest resolution to date. The work serves ...
Cell & Microbiology
Feb 13, 2023
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54
Small proteins called ferredoxins play a pivotal role in the main metabolic pathways, the series of chemical reactions occurring within a cell.
Cell & Microbiology
Feb 9, 2023
0
9
A groundbreaking technique for in-depth mapping of protein localizations in whole tissue developed by researchers in the University at Buffalo School of Pharmacy and Pharmaceutical Sciences has been published in Nature Communications.
Biotechnology
Feb 2, 2023
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15
Researchers have visualized the protein binding site of the (pro)renin receptor known to be involved in pancreatic cancer development using an artificial intelligence-based protein structure prediction program. They predicted ...
Cell & Microbiology
Dec 9, 2022
0
40
