Malaria, a mosquito-borne disease, killed more than 620,000 people worldwide in 2020. Jeopardizing the survival of Plasmodium falciparum, the malaria parasite, is one way to control the spread of this deadly disease.
Molecular & Computational biology
Mar 11, 2022
0
19
The amount of structural data on protein drug targets continues to grow. However, successfully mining this data to form testable hypotheses that drive drug discovery can prove challenging. Selectivity for the target protein ...
Biochemistry
Mar 2, 2022
0
11
The proteins that belong to the HAT family are essential for life as they transport amino acids across the cell membrane. Although the members of this family are practically identical, some transport certain amino acids and ...
Cell & Microbiology
Nov 29, 2021
0
98
The small GTPases of the ADP-ribosylation factor (Arf) family are key initiators of various physiological processes including secretion, endocytosis, phagocytosis and signal transduction. Arf family proteins function to mediate ...
Biochemistry
Jan 6, 2021
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7
A research group from the Department of Biochemistry and Molecular Biology of the University of Valencia (UV), in coordination with the National Center for Biotechnology (CNB) of the CSIC, has studied the role of the interactions ...
Biochemistry
Nov 30, 2020
0
6
A high concentration of salt or sugar in the environment will dehydrate microorganisms and stop them from growing. To counter this, bacteria can increase their internal solute concentration. Scientists from the University ...
Cell & Microbiology
Nov 18, 2020
0
103
Experts who study animal pheromones have traced the evolutionary origins of genes that allow mice, rats and other rodents to communicate through smell. The discovery is a clear example of how new genes can evolve through ...
Evolution
Sep 30, 2020
0
122
The recent coronavirus pandemic shows just how quickly a deadly pathogen can sweep across the globe, killing tens of thousands in the U.S. and disrupting daily life for millions more in the span of a few months. A lack of ...
Cell & Microbiology
May 18, 2020
0
4
DNA in a cell is comparable to tangled spaghetti strands on a plate. To be able to divide DNA neatly between the two daughter cells during cell division, the cell organises this tangle into tightly packed chromosomes. A protein ...
Biotechnology
Mar 5, 2020
3
57
In a paper published in the Journal of Biological Chemistry, Dr. Özdemir has studied two protein families named Rho GTPases and IQGAPs, which are known to play an important role in cancer metastasis. These two "suspicious" ...
Biochemistry
Apr 15, 2019
0
8
