A new screening method that can test the effectiveness of therapeutic molecules designed to 'glue' proteins together in the body has been developed by researchers at the University of Birmingham and the University of Leicester.
Biochemistry
Jul 7, 2021
0
19
Since the first known case of COVID-19 in December 2019, the disease has infected over 180 million people and killed nearly four million. A successful group of vaccines that target the coronavirus's spike protein has started ...
Molecular & Computational biology
Jul 6, 2021
0
5
Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world's population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a major threat to global health ...
Molecular & Computational biology
Jun 28, 2021
1
13
Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they're needed. As a proof of concept, the ...
Bio & Medicine
Jun 16, 2021
0
1306
Proteins are the essence of life: they give structure to cells and organelles, catalyze metabolic reactions, build, break, tug, and pull—they carry out most of the actions that sustain a cell's existence.
Biotechnology
Jun 9, 2021
0
10
Polypharmacology—the ability of a drug to affect more than one protein—should be studied early in the drug discovery pathway, and constantly monitored as the chemical structure is optimized in the design of the clinical ...
Biochemistry
Jun 2, 2021
0
6
In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic ...
Molecular & Computational biology
Jun 1, 2021
0
12
A cutting-edge digital tool that will make it cheaper, safer and faster for pharmaceutical companies to predict protein stability—a vital step in the development of new medicines—is being rolled out by scientists from ...
Biochemistry
May 27, 2021
0
8
In the search for treatments for COVID-19, many researchers are focusing their attention on a specific protein that allows the virus to infect human cells. This protein, which cells carry on their surface, is called angiotensin ...
Cell & Microbiology
May 5, 2021
0
13
Almost all bacteria rely on the same emergency valves—protein channels that pop open under pressure, releasing a deluge of cell contents. It is a last-ditch effort, a failsafe that prevents bacteria from exploding and dying ...
Molecular & Computational biology
Apr 13, 2021
0
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