A new study by chemists at the University of Arkansas shows that X-ray crystallography, the standard method for determining the structure of proteins, can provide inaccurate information about a critical set of proteins—those ...
Biochemistry
Oct 8, 2019
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94
Understanding the behavior of proteins and enzymes is key to unlocking the secrets of biological processes. The atomic structures of proteins are generally investigated using X-ray crystallography; however, the precise information ...
General Physics
Apr 27, 2020
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155
The COVID-19 pandemic, caused by the SARS CoV-2 virus, continues to threaten populations around the world, after killing over 1 million Americans. In recent weeks, XBB.1.5, the most transmissible variant to date, has started ...
Cell & Microbiology
Jan 10, 2023
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128
A device for precisely positioning small objects using acoustic waves has now been used to position fragile protein crystals a few micrometers or less in size in the path of a crystallography X-ray beam. This technique will ...
General Physics
Feb 6, 2015
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30
(Phys.org) —An international team of researchers, including LLNL physicist Matthias Frank and postdoc Mark Hunter, have for the first time used an ultra-intense X-ray laser to determine the previously unknown atomic-scale ...
General Physics
Mar 14, 2013
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0
(PhysOrg.com) -- University of Michigan physicists used the electric fields generated by intersecting laser beams to trap and manipulate thousands of microscopic plastic spheres, thereby creating 3-D arrays of optically induced ...
General Physics
Jun 1, 2011
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0
(Phys.org)—Using synchrotron x-ray beams to solve the molecular structures of proteins and other large biological molecules has yielded many advances in medicine, such as drug therapies for cancer. Improvements in the techniques ...
General Physics
Sep 6, 2012
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0
Researchers in Dana-Farber's cBio Center have now demonstrated a powerful 'experimental evolution' method to discover details of protein shape and function, and the method may find uses across a very broad spectrum of biomedical ...
Cell & Microbiology
Dec 11, 2019
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91
A team of scientists at University of Oxford have worked with multiple techniques at Diamond Light Source, to solve the structure of the influenza replication machinery and to determine how it interacts with cellular proteins. ...
Cell & Microbiology
Nov 4, 2022
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54
If you open any biology textbook to the section on proteins, you will learn that a protein is made up of a sequence of amino acids, that the sequence determines how the chain of amino acids folds into a compact structure, ...
Cell & Microbiology
Sep 20, 2012
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