Doing more with less; in cellulo structure determinations

Anyone involved in macromolecular crystallography will know that for many years scientists have had to rely on a multi-stage process utilizing protein, usually expressed in engineered cells, which is then extracted and purified ...

Researcher's protein crystal experiment set to fly to ISS

A University of Alabama in Huntsville (UAH) biology professor's experiment that is set to fly to the International Space Station (ISS) could shed new light on the roles enzymes play in biological processes.

Sometimes the average just isn't good enough

Computational biologists from the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna show that averaging is not always a good thing when it comes to analyzing protein crystal structures. ...

New insight into an emerging genome-editing tool

(Phys.org) —The potential is there for bacteria and other microbes to be genetically engineered to perform a cornucopia of valuable goods and services, from the production of safer, more effective medicines and clean, green, ...

Lessening X-ray damage is healthy for protein discovery data too

(Phys.org) —New recommendations for using X-rays promise to speed investigations aimed at understanding the structure and function of biologically important proteins – information critical to the development of new drugs. ...

Proteins' passing phases revealed

A new method to identify previously hidden details about the structures of proteins may speed the process of novel drug design, according to scientists at Rice University.

Bringing out the best in X-ray crystallography data

(Phys.org) —"Function follows form" might have been written to describe proteins, as the M. C. Escher-esque folds and twists of nature's workhorse biomolecules enables each to carry out its specific responsibilities. Technology's ...

Study finds new moves in protein's evolution

Highlighting an important but unexplored area of evolution, scientists at The Scripps Research Institute (TSRI) have found evidence that, over hundreds of millions of years, an essential protein has evolved chiefly by changing ...

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