Buried deep within the dazzlingly intricate machinery of the human cell could lie a key to treating a range of deadly cancers, according to a team of scientists at Florida State University.
Cell & Microbiology
Feb 26, 2019
0
96
Protein nanomachines made of multiple protein molecules are highly dynamic during their actions on their functional targets, sometime called substrates. Dynamics of these large protein nanomachines of more than megadalton ...
Biochemistry
Feb 26, 2019
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7
To perform the task for which they have been synthesized, proteins must first assemble to form effective cellular "machines." But how do they recognize their partners at the right time? Researchers at the University of Geneva ...
Cell & Microbiology
Jan 28, 2019
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17
One of a cell's most important responsibilities is to break down and recycle proteins that are no longer needed or endanger the cell. This task is carried out by a cellular nanomachine called the proteasome.
Cell & Microbiology
Dec 4, 2018
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25
Johns Hopkins researchers have found that the cellular "garbage disposal," known to scientists as proteasomes, may not only be responsible for the removal of cellular waste, but actually work on some of the most important ...
Cell & Microbiology
Jul 10, 2018
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4
New research from the Korea Institute of Science and Technology, to be published in the Journal of Biological Chemistry on Oct. 13, has found that the proteasome, an essential protein complex that breaks down proteins in ...
Biochemistry
Oct 10, 2017
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2
Cancer cells are more dependent on a cellular garbage disposal unit—the proteasome—than healthy cells, and cancer therapies take advantage of this dependency. Scientists at EMBL and MPI determined the proteasome's 3D ...
Biochemistry
Aug 4, 2016
0
872
Everyone would rather cook than take out the garbage. Perhaps that's why biochemists learned how cells make proteins 70 years ago, but are just now learning how they get rid of proteins that are no longer needed or no longer ...
Cell & Microbiology
Aug 1, 2016
1
35
Scientists have made a major breakthrough in the global search for a new drug to beat the malaria parasite's growing resistance to first-defence treatments.
Biochemistry
Feb 10, 2016
0
34
Meet a microscopic gymnast. A new study led by scientists at The Scripps Research Institute (TSRI) and the University of California (UC), Berkeley shows how a crucial molecular enzyme starts in a tucked-in somersault position ...
Cell & Microbiology
Jan 25, 2016
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