Researchers discover SARS-CoV-2 inhibitors

A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key ...

An evolutionary method for reprogramming proteases

A team of researchers affiliated with multiple institutions in the U.S. has developed an evolutionary method for reprogramming proteases. In their paper published in the journal Science, the group describes how their technique ...

Chemical compounds in foods can inhibit a key SARS-CoV-2 enzyme

Chemical compounds in foods or beverages like green tea, muscadine grapes and dark chocolate can bind to and block the function of a particular enzyme, or protease, in the SARS-CoV-2 virus, according to a new study by plant ...

How cells keep growing even when under attack

In an unexpected new finding, biochemists at the University of Massachusetts Amherst report observing that a damage-containment system in stressed bacteria can become overrun and blocked, but that this leads to cells responding ...

X-rays size up protein structure at the 'heart' of COVID-19 virus

A team of researchers at the Department of Energy's Oak Ridge and Argonne national laboratories has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease—the enzyme that enables the virus ...

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