Identifying a protein that plays a key role in cancer cell growth is a first step toward the development of a targeted cancer therapy. It is especially promising when this protein is dispensable for the growth of normal cells. ...
Biochemistry
Apr 19, 2019
0
129
From their birth through to their death, cells lead an eventful existence. Thanks to single-cell genomics, their destiny in large cell populations can now be analyzed. However, this method destroys the cell, which makes it ...
Cell & Microbiology
Apr 2, 2019
0
70
MicroRNAs (miRNAs) are short noncoding regulatory RNAs that can repress gene expression post-transcriptionally and are therefore increasingly used as biomarkers of disease. Detecting miRNAs can be arduous and expensive as ...
Lysophospholipids (LysoPLs) are potent cellular signaling biomolecules that also maintain the structure, shape and fluidity of cell membranes.
Oncology & Cancer
Feb 18, 2019
0
3
RUDN biochemists found a way to reduce the activity of telomerase (the enzyme of cell immortality) 10-fold. The discovery could lead to new antitumor drugs and give a better understanding of how the activity of the enzyme ...
Biochemistry
Feb 12, 2019
0
11
A recent study from the Laxman lab elucidates how a small metabolite and amino acid, methionine, acts as a growth signal for cells by setting into motion a metabolic program for cell proliferation.
Cell & Microbiology
Jan 7, 2019
0
4
Somatic stem cells are microscopic workhorses, constantly regenerating cells throughout the body: skin and the lining of the intestine, for example. And to University of Illinois neuroscientists, they represent untapped potential.
Cell & Microbiology
Oct 17, 2018
4
1544
Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein ...
Cell & Microbiology
Oct 1, 2018
0
70
Research about mechanical control of tissue development is published in Nature Communications this week. The article identifies the protein that regulates cell rearrangement in response to increasing tissue tension. This ...
Cell & Microbiology
Sep 10, 2018
0
9
Canadian researchers have discovered a new and direct molecular mechanism to stop cancer cells from proliferating. In the prestigious journal Nature Cell Biology, scientists from Université de Montréal show that a disruption ...
Cell & Microbiology
Jun 26, 2018
0
823
