It's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, ...
Cell & Microbiology
Jul 23, 2011
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Romping clumps of misfolded proteins are prime suspects in many neurological disorders including Alzheimer's, Parkinson's, and Creutzfeld-Jakob Disease. Those diseases are devastating and incurable, but a team of biologists ...
Cell & Microbiology
Mar 20, 2011
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(PhysOrg.com) -- North Carolina State University researchers have discovered a link between copper and the normal functioning of prion proteins, which are associated with transmissible spongiform encephalopathy diseases such ...
Biochemistry
Jun 25, 2009
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(PhysOrg.com) -- An investigation of a rare, inherited form of Creutzfeldt-Jakob disease suggests that disrupted regulation of copper ions in the brain may be a key factor in this and other prion diseases.
Biochemistry
Apr 17, 2009
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The discovery in common brewer's yeast of a new, infectious, misfolded protein -- or prion -- by University of Illinois at Chicago molecular biologists raises new questions about the roles played by these curious molecules, ...
Cell & Microbiology
Mar 13, 2009
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Chronic wasting disease, the prion disease affecting white-tailed deer and other cervids, is spreading. With documented cases in 29 U.S. states, two Canadian provinces, three Scandinavian countries, and South Korea, free-ranging ...
Ecology
Oct 11, 2022
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Two new studies coordinated by SISSA reveal important details about the physiological function of the prion protein, the non-pathological form of the notorious prion, the degenerate protein responsible for several diseases ...
Cell & Microbiology
Oct 17, 2016
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A team of Whitehead Institute and Stanford University scientists are redefining what it means to be a prion—a type of protein that can pass heritable traits from cell to cell by its structure instead of by DNA.
Biochemistry
Oct 4, 2016
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At the molecular level, the difference between Doctor Jekyll and Mr Hyde lies in a metal, copper. In its physiological form, the prion protein (PrPC ) is 'good' and is involved in normal body processes. It can happen, however, ...
Biochemistry
Oct 20, 2015
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Research by the University of Southampton has provided new insight into the consequence of accumulated 'misfolded proteins' in neurodegenerative disorders, such as Prion and Alzheimer's disease.
Biochemistry
Feb 14, 2014
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