Prion diseases are scary, incurable and fatal. They first gained notoriety when cows became infected by prion proteins and, in turn, infected people. Fervor surrounding mad cow disease resulted in the U.S. banning imports ...
Biochemistry
Mar 20, 2017
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Prions have a notorious reputation. They cause neurodegenerative disease, namely mad cow/Creutzfeld-Jakob disease. And the way these protein particles propagate—getting other proteins to join the pile—can seem insidious.
Cell & Microbiology
Jan 23, 2017
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12
Two new studies coordinated by SISSA reveal important details about the physiological function of the prion protein, the non-pathological form of the notorious prion, the degenerate protein responsible for several diseases ...
Cell & Microbiology
Oct 17, 2016
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5
A team of Whitehead Institute and Stanford University scientists are redefining what it means to be a prion—a type of protein that can pass heritable traits from cell to cell by its structure instead of by DNA.
Biochemistry
Oct 4, 2016
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1
Prion proteins, best known as the agents of deadly brain disorders like mad cow disease, can help yeast survive hard times and pass the advantageous traits down to their offspring, according to a new study by researchers ...
Biochemistry
Oct 3, 2016
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245
(Phys.org)—A team of researchers affiliated with the Whitehead Institute for Biomedical Research, MIT and the Howard Hughes Medical Institute, all in Massachusetts has found a prion-like protein in Arabidopsis thaliana, ...
At the molecular level, the difference between Doctor Jekyll and Mr Hyde lies in a metal, copper. In its physiological form, the prion protein (PrPC ) is 'good' and is involved in normal body processes. It can happen, however, ...
Biochemistry
Oct 20, 2015
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25
Workhorse molecules called heat-shock proteins contribute to refolding proteins that were once misfolded and clumped, causing such disorders as Parkinson's disease, amyotrophic lateral sclerosis, and Alzheimer's disease. ...
Cell & Microbiology
Jan 22, 2015
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60
Yeast cells can sometimes reverse the protein misfolding and clumping associated with diseases such as Alzheimer's, according to new research from the University of Arizona.
Cell & Microbiology
Dec 9, 2014
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2
Research by the University of Southampton has provided new insight into the consequence of accumulated 'misfolded proteins' in neurodegenerative disorders, such as Prion and Alzheimer's disease.
Biochemistry
Feb 14, 2014
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