News tagged with prion protein
Unravelling the mystery of misfolding prions
(Phys.org) -- Researchers at the University of Alberta's physics department and the National Institute for Nanotechnology (NINT) are the first to map out the folding pathways of prions, malformed ...
May 30, 2012 |
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Researchers develop novel technique for early detection of misfolded protein
(Phys.org) -- University of Delaware assistant professor David W. Colby is co-author of a paper in the March 23 issue of the Journal of Biological Chemistry that suggests protein misfolding may occur early in th ...
Apr 06, 2012 |
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Prion proteins play powerful role in survival, evolution of wild yeast strains
Prions, the much-maligned proteins most commonly known for causing "mad cow" disease, are commonly used in yeast to produce beneficial traits in the wild. Moreover, such traits can be passed on to subsequent generations and ...
Feb 15, 2012 |
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New study shows prions able to jump between species more easily than thought
(PhysOrg.com) -- A group of French researchers has found that prions are more easily able to jump between species than has been previously thought. In their paper published in Science, they show that prions ...
Jan 27, 2012 |
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Cellular stress can induce yeast to promote prion formation
It's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, ...
Jul 23, 2011 |
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Multitarget drugs against prion diseases
The central nervous systems of humans and cattle alike are attacked by prions (abnormal insoluble amyloidogenic proteins) when they suffer from Creutzfeldt–Jakob disease (CJD) or bovine spongiform encephalopathy ...
Mar 21, 2011 |
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Mutant prions help cells foil harmful protein misfolding
Romping clumps of misfolded proteins are prime suspects in many neurological disorders including Alzheimer's, Parkinson's, and Creutzfeld-Jakob Disease. Those diseases are devastating and incurable, but a team of biologists ...
Mar 20, 2011 |
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Needle-in-a-haystack search identifies potential brain disease drug
Scientists who examined more than 10,000 chemical compounds during the last year in search of potential new drugs for a group of untreatable brain diseases, are reporting that one substance shows unusual promise. The early ...
Medicine & Health / Medical research
Feb 23, 2011 |
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Unraveling how prion proteins move along axons in the brain
Researchers at the University of California, San Diego School of Medicine have identified the motors that move non-infectious prion proteins (PrPC) – found within many mammalian cells – up and down long, neuronal ...
Medicine & Health / Medical research
Feb 17, 2011 |
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Research identifies drug target for prion diseases, 'mad cow'
Scientists at the University of Kentucky have discovered that plasminogen, a protein used by the body to break up blood clots, speeds up the progress of prion diseases such as mad cow disease.
Medicine & Health / Medical research
Jan 10, 2011 |
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Scientists show prions mutate and adapt to host environment
Scientists from the Florida campus of The Scripps Research Institute have shown that prions, bits of infectious protein that can cause fatal neurodegenerative disease such as bovine spongiform encephalopathy (BSE) or "mad ...
Medicine & Health / Medical research
Dec 17, 2010 |
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Study suggests that early detection is possible for prion diseases
A fast test to diagnose fatal brain conditions such as mad cow disease in cattle and Creutzfeldt-Jakob disease in humans could be on the horizon, according to a new study from National Institutes of Health scientists. Researchers ...
Medicine & Health / Diseases, Conditions, Syndromes
Dec 02, 2010 |
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New prion discovery reveals drug target for mad cow disease and related illnesses
The joy of a juicy hamburger could make a comeback thanks a new discovery by scientists from the University of Kentucky. In a new research report in the December 2010 print issue of The FASEB Journal, scientists found that a ...
Medicine & Health / Medical research
Dec 01, 2010 |
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Size of protein aggregates, not abundance, drives spread of prion-based disease
Mad Cow disease and its human variant Creutzfeldt-Jakob disease, which are incurable and fatal, have been on a welcome hiatus from the news for years, but because mammals remain as vulnerable as ever to infectious diseases ...
Medicine & Health / Medical research
Oct 28, 2010 |
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New sporadic prion protein disease identified
A new sporadic prion protein disease has been discovered. Variably protease-sensitive prionopathy (VPSPr), as it has been named, is the second type of complete sporadic disease to be identified since Creutzfeldt-Jakob disease ...
Medicine & Health / Neuroscience
Aug 13, 2010 |
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PRNP
More reference expression data
PRNP (PRioN Protein (Creutzfeld-Jakob disease, Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia)) is a gene that codes for a protein called the prion protein (PrP), which is expressed in the brain and several other tissues.
The human PRNP gene is located on the short (p) arm of chromosome 20 between the end (terminus) of the arm and position 12, from base pair 4,615,068 to base pair 4,630,233.
PRNP has also recently been designated CD230 (cluster of differentiation 230).
For more information about PRNP, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
