News tagged with prion disease

Researchers develop novel technique for early detection of misfolded protein

(Phys.org) -- University of Delaware assistant professor David W. Colby is co-author of a paper in the March 23 issue of the Journal of Biological Chemistry that suggests protein misfolding may occur early in th ...

Chemistry / Biochemistry

created Apr 06, 2012 | popularity 5 / 5 (2) | comments 0

Ozone treated water v. lethal microbial material

A University of Alberta research team has discovered that technology commonly used to decontaminate food industry equipment can also rid meat processing plants of lethal microbial material responsible for the human version ...

Biology / Cell & Microbiology

created Mar 02, 2012 | popularity 5 / 5 (2) | comments 1

Prion proteins play powerful role in survival, evolution of wild yeast strains

Prions, the much-maligned proteins most commonly known for causing "mad cow" disease, are commonly used in yeast to produce beneficial traits in the wild. Moreover, such traits can be passed on to subsequent generations and ...

Biology / Cell & Microbiology

created Feb 15, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Cellular stress can induce yeast to promote prion formation

It's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, ...

Biology / Cell & Microbiology

created Jul 23, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Simulating amyloid formation

Many neurodegenerative diseases are characterized by proteins that assume an abnormal configuration, which leads to their aggregation and deposition in and around rve cells, causing cell death. This process, ...

Chemistry / Biochemistry

created May 04, 2011 | popularity 4 / 5 (1) | comments 0

Multitarget drugs against prion diseases

The central nervous systems of humans and cattle alike are attacked by prions (abnormal insoluble amyloidogenic proteins) when they suffer from Creutzfeldt–Jakob disease (CJD) or bovine spongiform encephalopathy ...

Chemistry / Biochemistry

created Mar 21, 2011 | popularity 5 / 5 (1) | comments 0

New research focuses on prion diseases

New research by Chongsuk Ryou, researcher at the UK Sanders-Brown Center on Aging and professor of microbiology, immunology and molecular genetics in the UK College of Medicine, may shed light on possible treatments for prion ...

Biology / Cell & Microbiology

created Mar 14, 2011 | popularity not rated yet | comments 0

BSE pathogens can be transmitted by air

Airborne prions are also infectious and can induce mad cow disease or Creutzfeldt-Jakob disorder. This is the surprising conclusion of researchers at the University of Zurich, the University Hospital Zurich and the University ...

Medicine & Health / Diseases, Conditions, Syndromes

created Jan 13, 2011 | popularity 5 / 5 (3) | comments 2

Research identifies drug target for prion diseases, 'mad cow'

Scientists at the University of Kentucky have discovered that plasminogen, a protein used by the body to break up blood clots, speeds up the progress of prion diseases such as mad cow disease.

Medicine & Health / Medical research

created Jan 10, 2011 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Scientists show prions mutate and adapt to host environment

Scientists from the Florida campus of The Scripps Research Institute have shown that prions, bits of infectious protein that can cause fatal neurodegenerative disease such as bovine spongiform encephalopathy (BSE) or "mad ...

Medicine & Health / Medical research

created Dec 17, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study suggests that early detection is possible for prion diseases

A fast test to diagnose fatal brain conditions such as mad cow disease in cattle and Creutzfeldt-Jakob disease in humans could be on the horizon, according to a new study from National Institutes of Health scientists. Researchers ...

Medicine & Health / Diseases, Conditions, Syndromes

created Dec 02, 2010 | popularity 5 / 5 (1) | comments 0

New prion discovery reveals drug target for mad cow disease and related illnesses

The joy of a juicy hamburger could make a comeback thanks a new discovery by scientists from the University of Kentucky. In a new research report in the December 2010 print issue of The FASEB Journal, scientists found that a ...

Medicine & Health / Medical research

created Dec 01, 2010 | popularity 4 / 5 (1) | comments 0

Size of protein aggregates, not abundance, drives spread of prion-based disease

Mad Cow disease and its human variant Creutzfeldt-Jakob disease, which are incurable and fatal, have been on a welcome hiatus from the news for years, but because mammals remain as vulnerable as ever to infectious diseases ...

Medicine & Health / Medical research

created Oct 28, 2010 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

New sporadic prion protein disease identified

A new sporadic prion protein disease has been discovered. Variably protease-sensitive prionopathy (VPSPr), as it has been named, is the second type of complete sporadic disease to be identified since Creutzfeldt-Jakob disease ...

Medicine & Health / Neuroscience

created Aug 13, 2010 | popularity 4.8 / 5 (4) | comments 0

Study shows infectious prions can arise spontaneously in normal brain tissue

In a startling new study that involved research on both sides of the Atlantic, scientists from The Scripps Research Institute in Florida and the University College London (UCL) Institute of Neurology in England have shown ...

Medicine & Health / Medical research

created Jul 26, 2010 | popularity 3.7 / 5 (6) | comments 1 | with audio podcast