News tagged with primary cilium
Mysterious cilium functions as cellular communication hub, study shows
(PhysOrg.com) -- Nearly all mammalian cells have what's called a primary cilium -- a single, stump-like rod projecting from the smooth contours of the cell's outer membrane. Unlike its more flamboyant cousins, the motile ...
Jun 24, 2010 |
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Some brain tumors may be mediated by tiny filament on cells
UCSF scientists have discovered that a tiny filament extending from cells, until recently regarded as a remnant of evolution, may play a role in the most common malignant brain tumor in children.
Aug 23, 2009 |
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Search results for primary cilium
Genetic sequencing alone doesn't offer a true picture of human disease
Despite what you might have heard, genetic sequencing alone is not enough to understand human disease. Researchers at Duke University Medical Center have shown that functional tests are absolutely necessary to understand ...
Jan 23, 2011 |
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Man's best friend helps to solve puzzle of a genetic disorder
(PhysOrg.com) -- Observations in purebred dogs led an international team of scientists from Duke University Medical Center and other institutions to make an important gene discovery in a devastating human genetic condition ...
Dec 06, 2010 |
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Arsenic shows promise as cancer treatment, study finds
Miss Marple notwithstanding, arsenic might not be many people's favorite chemical. But the notorious poison does have some medical applications. Specifically, a form called arsenic trioxide has been used as a therapy for ...
Jul 12, 2010 |
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Researchers demystifying complex cellular communications hubs found in sensory neurons
It's safe to say that cilia, the hairlike appendages jutting out from the smooth surfaces of most mammalian cells, have long been misunderstood - underestimated, even.
Jul 07, 2010 |
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Using fish to illuminate the architecture of inherited disease
A research team led by scientists from the Duke University Medical Center has developed a way to simultaneously look at the effects of 125 mutations occurring on 14 different genes. They used zebrafish as a model to analyze ...
May 24, 2010 |
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Primary cilia formation provides insight into genetic diseases
A team of scientists at the University of California, San Diego School of Medicine have identified a network of genes that initiate and manage cilia formation. Although scientists have known about cilia for decades, only ...
Medicine & Health / Medical research
Apr 14, 2010 |
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Antifungal medicine shown to slow tumor growth in mice study
(PhysOrg.com) -- A common antifungal medication can slow tumor growth in mice, according to scientists at the Stanford University School of Medicine. The drug, called itraconazole, inhibits a molecular pathway important during ...
Apr 12, 2010 |
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Diffusion of a soluble protein through a sensory cilium
A team of researchers led by Peter Calvert (SUNY Upstate Medical University) has, for the first time, measured the diffusion coefficient of a protein in a primary cilium and in other major compartments of ...
Medicine & Health / Medical research
Feb 22, 2010 |
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Some skin cancer may be mediated by primary cilia activity
Tiny, solitary spikes that stick out of nearly every cell in the body play a central role in a type of skin cancer, new research has found. The discovery in mice shows that the microscopic structures known as primary cilia ...
Aug 23, 2009 |
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Mutations in gene linked to ciliopathies
An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, have discovered a connection between mutations in the INPP5E gene and ciliopathies. Their findings, which ...
Aug 09, 2009 |
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List of search results for primary cilium