News tagged with polymerase
New details about gene regulation explained
(Phys.org) -- When genetic information is read from the genetic blueprint DNA, RNA polymerase II translates it into RNA molecules. The C-terminal domain, abbreviated as CTD, is an important area of the polymerase ...
May 21, 2012 |
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Bioluminescent technology for easy tracking of GMO
It is important to be able to monitor genetically modified (GM) crops, not only in the field but also during the food processing chain. New research published in BioMed Central's open access journal BMC Biotechnology shows ...
Apr 30, 2012 |
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Everything flows in rapid diagnostic tests
(Phys.org) -- Our ability to detect pathogens has become quite good, but it usually requires complex laboratory techniques. Sometimes we need a quick result, or there is no laboratory nearby. Portable and ...
Chemistry / Analytical Chemistry
Apr 12, 2012 |
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New technology sheds light on viruses
(Phys.org) -- Diagnostic tests that rapidly detect disease-causing viruses in animals and humans are being developed by U.S. Department of Agriculture (USDA) scientists using a new technology called "surface-enhanced ...
Chemistry / Analytical Chemistry
Apr 10, 2012 |
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Biologists offer clearer picture of how protein machine systems tweak gene expression
Indiana University biologists have found that specific types of RNA polymerase enzymes, the molecular machines that convert DNA into RNA, can differ in function based on variation in the parts -- in this case ...
Mar 01, 2012 |
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Research into possible Woodchester wild cat finds no cat DNA on deer
Extensive DNA tests by experts at the University of Warwick on two deer carcasses found in Gloucestershire have not found any indication of a big cat presence.
Feb 01, 2012 |
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Study uncovers how DNA unfolds for transcription
(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human genome would ...
Jan 17, 2012 |
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Transcriptional elongation control takes on new dimensions
Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in ...
Dec 22, 2011 |
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Researchers demonstrate new DNA detection technique
A team of researchers from the University of Notre Dame have demonstrated a novel DNA detection method that could prove suitable for many real-world applications.
Dec 16, 2011 |
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Nanoparticles and Mini-NMR point the way to personalized cancer therapy
(PhysOrg.com) -- With the advent of targeted drug therapy for treating cancer, it has become clear that an important predictor of success of these therapies is whether such a drug is reaching its target in the patient. The ...
Nanotechnology / Bio & Medicine
Nov 21, 2011 |
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Test identifies Red Angus carriers of bone disease
A new test that detects a rare and deadly bone disorder in Red Angus is now available to cattle producers, thanks to U.S. Department of Agriculture (USDA) scientists.
Sep 29, 2011 |
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Structure of a molecular copy machine: How mitochondrial genes are transcribed
Mitochondria are compartments within cells and have their own DNA. The key protein required for the expression of the genetic information in this DNA is the mitochondrial RNA polymerase enzyme. Its three-dimensional structure ...
Sep 26, 2011 |
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CSI: PCR-free techniques ID the most active microbes on the scene
Anyone who has watched one of the CSI: Crime Scene Investigation television shows knows that PCR (Polymerase Chain Reaction) is a technology used to amplify the tiniest samples of DNA into forensic evidence ...
Sep 21, 2011 |
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Dundee researchers make gene breakthrough
Researchers at the University of Dundee have made a significant breakthrough in understanding how human cells decode genes important for cell growth and multiplication.
Sep 16, 2011 |
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A better test for a potato pest
A U.S. Department of Agriculture (USDA) scientist has created a new weapon in the war being waged against the potato cyst nematode-a diagnostic test that identifies the type of nematode infesting a grower's field.
Aug 23, 2011 |
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Polymerase
A polymerase (EC 2.7.7.6/7/19/48/49) is an enzyme whose central function is associated with polymers of nucleic acids such as RNA and DNA. The primary function of a polymerase is the polymerization of new DNA or RNA against an existing DNA or RNA template in the processes of replication and transcription. In association with a cluster of other enzymes and proteins, they take nucleotides from solvent, and catalyse the synthesis of a polynucleotide sequence against a nucleotide template strand using base-pairing interactions.
It is an accident of history that the enzymes responsible for the catalytic production of other biopolymers are not also referred to as polymerases.
One particular polymerase, from the thermophilic bacterium, Thermus aquaticus (Taq) (PDB 1BGX, EC 2.7.7.7) is of vital commercial importance due to its use in the polymerase chain reaction, a widely used technique of molecular biology.
Other well-known polymerases include:
For more information about Polymerase, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
