News tagged with polymerase ii
New details about gene regulation explained
(Phys.org) -- When genetic information is read from the genetic blueprint DNA, RNA polymerase II translates it into RNA molecules. The C-terminal domain, abbreviated as CTD, is an important area of the polymerase ...
May 21, 2012 |
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Biologists offer clearer picture of how protein machine systems tweak gene expression
Indiana University biologists have found that specific types of RNA polymerase enzymes, the molecular machines that convert DNA into RNA, can differ in function based on variation in the parts -- in this case ...
Mar 01, 2012 |
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Study uncovers how DNA unfolds for transcription
(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human genome would ...
Jan 17, 2012 |
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Transcriptional elongation control takes on new dimensions
Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in ...
Dec 22, 2011 |
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Ready, go!
Just like orchestra musicians waiting for their cue, RNA polymerase II molecules are poised at the start site of many developmentally controlled genes, waiting for the "Go!"- signal to read their part of the ...
Jul 14, 2011 |
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Stop and go: How the cell deals with transcriptional roadblocks
Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis. The enzyme RNA polymerase II (Pol II) is responsible ...
Feb 23, 2011 |
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Correcting a trick of the light brings molecules into view
Conventional wisdom holds that optical microscopy can't be used to "see" something as small as an individual molecule. But as it is wont, clever science has once again overturned conventional wisdom. Secretary ...
Jul 14, 2010 |
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How the wrong genes are repressed
The mechanism by which 'polycomb' proteins critical for embyronic stem cell function and fate are targeted to DNA has been identified by UCL scientists.
Jun 11, 2010 |
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How RNA polymerase II gets the go-ahead for gene transcription
All cells perform certain basic functions. Each must selectively transcribe parts of the DNA that makes up its genome into RNAs that specify the structure of proteins. The set of proteins synthesized by a cell in turn determines ...
Oct 09, 2009 |
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Gene transcribing machine takes halting, backsliding trip along the DNA
(PhysOrg.com) -- The body's nanomachines that read our genes don't run as smoothly as previously thought, according to a new study by University of California, Berkeley, scientists.
Jul 30, 2009 |
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Plant polymerases IV and V are special forms of Polymerase II
(PhysOrg.com) -- It's a little like finding out that Superman is actually Clark Kent. A team of biologists at Washington University in St. Louis has discovered that two vital cellular components, nuclear RNA ...
Biology /
Jan 06, 2009 |
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