Stay out, stray stem cells
Despite the hubbub about pluripotent stem cells' potential applications, when it comes time to introduce products into patients, the stem cells are actually impurities that need to be removed.
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Directly reprogramming a cell's identity with gene editing
Researchers have used CRISPR—a revolutionary new genetic engineering technique—to convert cells isolated from mouse connective tissue directly into neuronal cells.
First report on efficient reprogramming of diabetic foot ulcer cells to create therapeutic stem cell
The potential to use a patient's own cells to treat non-healing chronic wounds - a serious complication of diabetes - took an important step forward as researchers successfully reprogrammed skin cells taken from diabetic ...
Scientists develop new way to measure important chemical modification on RNA
A team of scientists including researchers from UCLA has developed an RNA sequencing technique that provides detailed information about a chemical modification that occurs on RNA and plays an important role in pluripotent ...
Scientists discover a way to create specialized cells more efficiently
Researchers at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have discovered that a metabolic molecule called alpha-ketoglutarate helps pluripotent stem cells mature early in the process ...
Breakthrough in scaling up life-changing stem cell production
Scientists have discovered a new method of creating human stem cells which could solve the big problem of the large-scale production needed to fully realise the potential of these remarkable cells for understanding and treating ...
How much do you know about Dolly the Sheep?
This week marked the 20th anniversary of the birth of arguably the most famous sheep that ever chewed grass. Dolly was created at The Roslin Institute, Scotland, which receives long-term strategic funding from BBSRC.
Scientists confirm reprogrammed adult stem cells identical to embryonic stem cells
Researchers from the Vavilov Institute of General Genetics, Research Institute of Physical Chemical Medicine and Moscow Institute of Physics and Technology (MIPT) have concluded that reprogramming does not create differences ...
Study sets standards for evaluating pluripotent stem cell quality
As the promise of using regenerative stem cell therapies draws closer, a consortium of biomedical scientists reports about 30 percent of induced pluripotent stem cells they analyzed from 10 research institutions were genetically ...
Bioengineers show why lab-made stem cells might fail: Errors in DNA folding
Induced pluripotent stem cells hold promise for regenerative medicine because they can, in theory, turn into any type of tissue and because they are made from a patient's own adult cells, guaranteeing compatibility. However, ...
