News tagged with phosphorylation
DNA 'molecular scissors' discovered
(PhysOrg.com) -- Scientists at the University of Dundee have discovered a protein that acts as a 'molecular scissors' to repair damaged DNA in our cells, a finding which could have major implications for cancer treatments.
Jul 09, 2010 |
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Cancers' sweet tooth may be weakness
The pedal-to-the-metal signals driving the growth of several types of cancer cells lead to a common switch governing the use of glucose, researchers at Winship Cancer Institute of Emory University have discovered.
Nov 18, 2009 |
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What makes stem cells tick?
Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...
Aug 06, 2009 |
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Different evolutionary paths lead plants and animals to the same crossroads
In analyzing the molecular sensor for the plant growth hormone brassinolide, researchers at the Salk Institute for Biological Studies discovered that although plants took an evolutionary path different from ...
Jan 31, 2011 |
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Key enzyme discovered to be master regulator in protein-protein reactions
Protein phosphorylation is a process by which proteins are flipped from one activation state to another. It is a crucial function for most living beings, since phosphorylation controls nearly every cellular ...
Mar 24, 2010 |
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Building memories with actin
Memories aren't made of actin filaments. But their assembly is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. In the July 13, ...
Jul 13, 2009 |
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Chronic kidney disease linked to malfunctioning mitochondria
Chronic kidney disease (CKD) has been linked to oxidative stress caused by dysregulation of the genes that control mitochondria. A study in the open access journal BMC Genomics has revealed alterations in respiration gene e ...
Medicine & Health / Diseases, Conditions, Syndromes
Aug 20, 2009 |
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Research reveals how blood flow force protects blood vessels
It is second nature for most of us that exercise protects against heart attack and stroke, but researchers have spent 30 years unraveling the biochemistry behind the idea. One answer first offered by researchers at the University ...
Medicine & Health / Medical research
Jan 28, 2010 |
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Boon to plant science
In both plant and animal cells, protein activity is often regulated by phosphorylation, by which a phosphate group is added to one or more sites on a protein. A team led by Ken Shirasu of RIKEN Plant Science ...
Aug 30, 2010 |
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Parkinson's disease may be caused by microtubule, rather than mitochondrial complex I, dysfunction
Patients with Parkinson's disease (PD) suffer a specific loss of dopaminergic neurons from the midbrain region that controls motor function. The exact mechanism of this selective neurodegeneration is unclear, ...
Mar 07, 2011 |
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Molecular spectroscopy tracks living mammalian cells in real time as they differentiate
Knowing how a living cell works means knowing how the chemistry inside the cell changes as the functions of the cell change. Protein phosphorylation, for example, controls everything from cell proliferation ...
Chemistry / Analytical Chemistry
Apr 30, 2012 |
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Researchers identify one of the necessary processes in the formation of long-term memory
A new study that was carried out at the University of Haifa has identified another component in the chain of actions that take place in the neurons in the process of forming memories. This discovery joins a line of findings ...
Medicine & Health / Neuroscience
Sep 08, 2009 |
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When cancer cells can't let go
Like a climber scaling a rock face, a migrating cancer cell has to keep a tight grip on the surface but also let go at the right moment to move ahead. Chan et al. reveal that the focal adhesion kinase (FAK) ...
Apr 13, 2009 |
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Phosphorylation
Phosphorylation is the addition of a phosphate (PO43-) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes.
Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2009, the Medline database returns nearly 160,000 articles on the subject, largely on protein phosphorylation).
For more information about Phosphorylation, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
