News tagged with phosphorylation
Research reveals how blood flow force protects blood vessels
It is second nature for most of us that exercise protects against heart attack and stroke, but researchers have spent 30 years unraveling the biochemistry behind the idea. One answer first offered by researchers at the University ...
Medicine & Health / Medical research
Jan 28, 2010 |
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IKK may act as both inhibitor and promoter of Huntington's disease
The kinase IKK phosphorylates the protein mutated in Huntington's disease to promote its removal and neuron survival, but IKK may be a double-edged sword that increases neurotoxicity in later stages of the disease. The study, ...
Dec 21, 2009 |
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Cancers' sweet tooth may be weakness
The pedal-to-the-metal signals driving the growth of several types of cancer cells lead to a common switch governing the use of glucose, researchers at Winship Cancer Institute of Emory University have discovered.
Nov 18, 2009 |
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A balancing act in Parkinson's disease: Phosphorylation of alpha-synuclein
Both genetic and pathologic data indicate a role for the neuronal protein alpha-synuclein in Parkinson disease. Previous studies have indicated that phosphorylation of alpha-synuclein at amino acid 129 (Ser129) is a key event ...
Medicine & Health / Medical research
Oct 12, 2009 |
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Researchers identify one of the necessary processes in the formation of long-term memory
A new study that was carried out at the University of Haifa has identified another component in the chain of actions that take place in the neurons in the process of forming memories. This discovery joins a line of findings ...
Medicine & Health / Neuroscience
Sep 08, 2009 |
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Chronic kidney disease linked to malfunctioning mitochondria
Chronic kidney disease (CKD) has been linked to oxidative stress caused by dysregulation of the genes that control mitochondria. A study in the open access journal BMC Genomics has revealed alterations in respiration gene e ...
Medicine & Health / Diseases, Conditions, Syndromes
Aug 20, 2009 |
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Mighty mice: Treatment targeted to muscle improves motor neuron disease
New research with transgenic mice reveals that a therapy directed at the muscle significantly improves disease symptoms of a genetic disorder characterized by destruction of the neurons that control movement. The study, published ...
Medicine & Health / Neuroscience
Aug 12, 2009 |
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What makes stem cells tick?
Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...
Aug 06, 2009 |
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Phase 3 Alzheimer's drug increases toxic beta amyloid in the brain -- but still provides benefits
New insights into how a Phase III Alzheimer's drug might work were among the advances in potential therapies targeting two abnormal brain proteins - beta amyloid and phosphorylated tau - that were reported today at the Alzheimer's ...
Medicine & Health / Diseases, Conditions, Syndromes
Jul 15, 2009 |
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Building memories with actin
Memories aren't made of actin filaments. But their assembly is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. In the July 13, ...
Jul 13, 2009 |
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Protein can help cells or cause cancer, researcher finds
A Purdue University scientist has discovered a key process in cell growth that can lead to the formation of tumors.
Jul 07, 2009 |
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When cancer cells can't let go
Like a climber scaling a rock face, a migrating cancer cell has to keep a tight grip on the surface but also let go at the right moment to move ahead. Chan et al. reveal that the focal adhesion kinase (FAK) ...
Apr 13, 2009 |
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