News tagged with phosphorylated proteins
Molecular spectroscopy tracks living mammalian cells in real time as they differentiate
Knowing how a living cell works means knowing how the chemistry inside the cell changes as the functions of the cell change. Protein phosphorylation, for example, controls everything from cell proliferation ...
Chemistry / Analytical Chemistry
Apr 30, 2012 |
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Proteomics identifies targets of ionizing radiation in a human skin model
(Phys.org) -- How better to find out what effect ionizing radiation has on human skin than by using the real thing? Researchers at Pacific Northwest National Laboratory did that by performing a quantitative ...
Apr 24, 2012 |
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New insights for a therapeutic approach in glioblastoma
(PhysOrg.com) -- Scientists from the Friedrich Miescher Institute for Biomedical Research have identified a new and important molecular player in glioblastoma. The amount of the MNK1 kinase is not only dramatically ...
Mar 18, 2011 |
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Purdue startup hopes to change the way we test cancer drugs
A Purdue University scientist's nanopolymer would make it easier and cheaper for drug developers to test the effectiveness of a widely used class of cancer inhibitors.
Chemistry / Analytical Chemistry
Mar 16, 2011 |
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Marine bacteria cope with harsh mileu, learn to adapt
Marine bacteria live in a harsh mileu. They must constantly cope and adapt to changes in salinity, pH, temperature and other parameters. In her thesis, Barbara Weber, Umea University, studied how bacteria communicate with ...
Sep 07, 2010 |
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Boon to plant science
In both plant and animal cells, protein activity is often regulated by phosphorylation, by which a phosphate group is added to one or more sites on a protein. A team led by Ken Shirasu of RIKEN Plant Science ...
Aug 30, 2010 |
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DNA 'molecular scissors' discovered
(PhysOrg.com) -- Scientists at the University of Dundee have discovered a protein that acts as a 'molecular scissors' to repair damaged DNA in our cells, a finding which could have major implications for cancer treatments.
Jul 09, 2010 |
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Key enzyme discovered to be master regulator in protein-protein reactions
Protein phosphorylation is a process by which proteins are flipped from one activation state to another. It is a crucial function for most living beings, since phosphorylation controls nearly every cellular ...
Mar 24, 2010 |
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IKK may act as both inhibitor and promoter of Huntington's disease
The kinase IKK phosphorylates the protein mutated in Huntington's disease to promote its removal and neuron survival, but IKK may be a double-edged sword that increases neurotoxicity in later stages of the disease. The study, ...
Dec 21, 2009 |
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Mighty mice: Treatment targeted to muscle improves motor neuron disease
New research with transgenic mice reveals that a therapy directed at the muscle significantly improves disease symptoms of a genetic disorder characterized by destruction of the neurons that control movement. The study, published ...
Medicine & Health / Neuroscience
Aug 12, 2009 |
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What makes stem cells tick?
Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...
Aug 06, 2009 |
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Phase 3 Alzheimer's drug increases toxic beta amyloid in the brain -- but still provides benefits
New insights into how a Phase III Alzheimer's drug might work were among the advances in potential therapies targeting two abnormal brain proteins - beta amyloid and phosphorylated tau - that were reported today at the Alzheimer's ...
Medicine & Health / Diseases, Conditions, Syndromes
Jul 15, 2009 |
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Protein can help cells or cause cancer, researcher finds
A Purdue University scientist has discovered a key process in cell growth that can lead to the formation of tumors.
Jul 07, 2009 |
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When cancer cells can't let go
Like a climber scaling a rock face, a migrating cancer cell has to keep a tight grip on the surface but also let go at the right moment to move ahead. Chan et al. reveal that the focal adhesion kinase (FAK) ...
Apr 13, 2009 |
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