Sustainable synthesis method reveals N-hydroxy modifications for pharmaceuticals
Recently published research results enable preparative access to novel substances that carry a modification of a structural motif frequently found in pharmaceuticals.
Recently published research results enable preparative access to novel substances that carry a modification of a structural motif frequently found in pharmaceuticals.
Analytical Chemistry
Apr 16, 2024
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44
Proteins not only carry out the functions that are critical for the survival of cells, but also influence the development and progression of diseases. To understand their role in health and disease, researchers study the ...
Molecular & Computational biology
Mar 1, 2024
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65
Researchers have developed a "self-driving" lab that uses artificial intelligence (AI) and automated systems to provide in-depth analyses of catalytic reactions used in chemical research and manufacturing. The new tool, called ...
Analytical Chemistry
Feb 27, 2024
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64
Researchers have shown it is possible to image small animal tissue clearly to several hundred micrometers using multi-probe imaging, reports a recent study in Scientific Reports.
Biochemistry
Dec 27, 2023
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2
Most diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great ...
Biochemistry
Dec 11, 2023
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57
Microgels form a thin protective shell around a droplet until the temperature rises above 32°C. Then the microgels shrink and the droplet dissolves in the surrounding liquid. A study by researchers from the University of ...
Soft Matter
Nov 30, 2023
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15
Researchers at the University of Eastern Finland School of Pharmacy have developed a new method for the accurate determination of the water content of water-soluble compounds. This plays a significant role in, for example, ...
Analytical Chemistry
Nov 21, 2023
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1
Scientists have long understood that parts of cells, called organelles, evolved to have certain shapes and sizes because their forms are closely related to how they function. Now, Johns Hopkins researchers have developed ...
Cell & Microbiology
Sep 27, 2023
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33
Membrane proteins play a pivotal role in various cellular functions and are key targets for pharmaceutical interventions. In fact, approximately 60% of drugs currently available on the market target these specific proteins. ...
Molecular & Computational biology
Sep 7, 2023
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1
A study conducted by researchers from the University of Chemistry and Technology in Prague sheds light on the properties and performance of dry-coated paracetamol particles, utilizing carnauba wax as the coating agent. The ...
Biochemistry
Aug 9, 2023
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12