Surprise discovery set to improve drug development

A surprising discovery from the University of Virginia School of Medicine has torpedoed a key principle used in the development of new drugs to treat diseases. The finding could speed the drug-development process and help ...

How TFIIH uses XPG to located damaged DNA

Nucleotide excision repair (NER) is a critical DNA repair pathway that plays a key role in maintaining transcription and genome integrity by removing bulky DNA lesions.

Researchers discover new form of antimicrobial resistance

Australian researchers have uncovered a new form of antimicrobial resistance (AMR), undetectable using traditional laboratory testing methods, in a discovery set to challenge existing efforts to monitor and tackle one of ...

Why some feces float and others sink

A team of researchers at the Mayo Clinic has solved the mystery of why some people find their bowel movements floating while others find theirs sinking to the bottom of the toilet bowl. In their paper published in the journal ...

Copper a clue in the fight against cancer

For cancer cells to grow and spread around the human body, they need proteins that bind copper ions. New research about how cancer-related proteins bind the metal and how they interact with other proteins, opens up potential ...

Are COVID 'comas' signs of a protective hibernation state?

Many COVID-19 patients who have been treated for weeks or months with mechanical ventilation have been slow to regain consciousness even after being taken off sedation. A new article in the Proceedings of the National Academy ...

Preventing resistance in cancer therapy

The latest developmental drugs, particularly for use in oncology, rely on the targeted degradation of harmful pathogenic proteins. In a recent study published in Nature Chemical Biology, researchers at CeMM, the Research ...

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