News tagged with pathway deregulation
Addition of dasatinib to standard chemo cocktail may enhance effect in certain ovarian cancers
The addition of a chemotherapeutic drug for leukemia to a standard regimen of two other chemotherapy drugs appears to enhance the response of certain ovarian cancers to treatment, according to a pre-clinical study led by ...
Apr 19, 2009 |
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Search results for pathway deregulation
Researchers unravel protein's elusive role in embryo and disease development
Reporting in Nature, scientists from Thomas Jefferson University have determined that a single protein called FADD controls multiple cell death pathways, a discovery that could lead to better, more targeted autoimmune diseas ...
Medicine & Health / Medical research
Mar 02, 2011 |
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New study finds molecular mechanisms that control Rb2/p130 gene expression in lung cancer
Despite innumerable studies on lung cancer, many aspects of the disease have yet to be understood, including the role played by the retinoblastoma-related protein Rb2/p130 in the evolution of the disease.
Feb 25, 2011 |
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Couch potatoes beware: Too much time spent watching TV is harmful to heart health
Spending too much leisure time in front of a TV or computer screen appears to dramatically increase the risk for heart disease and premature death from any cause, perhaps regardless of how much exercise one gets, according ...
Jan 10, 2011 |
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How cells running on empty trigger fuel recycling
Researchers at the Salk Institute for Biological Studies have discovered how AMPK, a metabolic master switch that springs into gear when cells run low on energy, revs up a cellular recycling program to free ...
Medicine & Health / Medical research
Dec 23, 2010 |
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Ovarian cancer advances when genes are silenced
There are many mechanisms that alter the activity of genes – direct changes to the DNA code like mutations and deletions, or changes that control when genes are switched on and off, called epigenetic means. Tumor-suppressor ...
Dec 13, 2010 |
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Discovery of a mechanism that controls the expression of a protein involved in numerous cancers
(PhysOrg.com) -- Researchers at the Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal have identified a new mechanism controlling the transmission of an abnormal signal at the ...
Oct 19, 2010 |
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A molecular warning sign of dementia?
A study of mice entering their twilight years has identified specific changes in the brain that impair these elderly mice during learning—and researchers say that their findings might benefit people struggling with age-related ...
Medicine & Health / Medical research
May 07, 2010 |
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Cross Talk Between Oncogenes Suggests Treatment Combination in Esophageal Cancer
(PhysOrg.com) -- Using a three-dimensional tissue culture system that mimics esophageal tissue growth of the particularly aggressive type of tumors known as ESCC (esophageal squamous cell cancer), Penn researchers have discovered ...
Apr 20, 2010 |
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New gene in hair loss identified
A team of investigators from Columbia, Rockefeller and Stanford Universities has identified a new gene involved in hair growth, as reported in a paper in the April 15 issue of Nature. This discovery may affect future resear ...
Apr 14, 2010 |
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Researchers discover new approach for identifying smokers at highest risk for developing lung cancer
Researchers from Boston University School of Medicine (BUSM) in collaboration with investigators at the University of Utah, have discovered a new approach for identifying smokers at the highest risk for developing lung cancer. ...
Apr 07, 2010 |
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List of search results for pathway deregulation
