News tagged with p53

Scientists show TAp63 suppresses cancer metastasis

Long overshadowed by p53, its famous tumor-suppressing sibling, the p63 gene does the tougher, important job of stifling the spread of cancer to other organs, researchers at The University of Texas MD Anderson Cancer Center ...

Oct 20, 2010
5 / 5 (5) 0 | with audio podcast

Newly discovered gene plays vital role in cancer

(PhysOrg.com) -- Gene p53 protects against cancer and is usually described as the most important gene in cancer research. However, scientists at the Swedish medical university Karolinska Institutet have now shown that a previously ...

Feb 27, 2009
4.8 / 5 (8) 0

A chaperone for the 'guardian of the genome'

The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...

Sep 07, 2011
5 / 5 (3) 0 | with audio podcast

Novel compound selectively kills cancer cells

A cancer cell may seem out of control, growing wildly and breaking all the rules of orderly cell life and death. But amid the seeming chaos there is a balance between a cancer cell's revved-up metabolism and skyrocketing ...

Jul 13, 2011
4.9 / 5 (9) 1 | with audio podcast