News tagged with p53

Eggs' quality control mechanism explained

To protect the health of future generations, body keeps a careful watch on its precious and limited supply of eggs. That's done through a key quality control process in oocytes (the immature eggs), which ensures elimination ...

Feb 17, 2011
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Researchers discover potential cancer therapy target

One of the most important genes in the human genome is called p53 and its function is to suppress tumours, according to Roger Leng, a researcher in the Faculty of Medicine & Dentistry. Leng has discovered the mechanism by ...

Feb 14, 2011
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Cancer cell survival is not 'miR-ly' dependent on p53

Squamous cell carcinoma (SCC) is a common type of skin cancer. In this paper, Leif Ellisen and colleagues at Mass General Hospital investigated the p53-related proteins p63 and p73 in SCC cells, and discovered a feedback ...

Jan 10, 2011
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p53 determines organ size

In studies conducted on the fruit fly, researchers at IRB Barcelona (Spain) headed by ICREA Professor Marco Milan have revealed that organs have the molecular mechanisms to control their proportions. In this process the protein ...

Dec 15, 2010
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Scientists show TAp63 suppresses cancer metastasis

Long overshadowed by p53, its famous tumor-suppressing sibling, the p63 gene does the tougher, important job of stifling the spread of cancer to other organs, researchers at The University of Texas MD Anderson Cancer Center ...

Oct 20, 2010
5 / 5 (5) 0 | with audio podcast

MicroRNA to combat cancer

(PhysOrg.com) -- Researchers from the Queensland Institute of Medical Research, the Garvan Institute of Medical Research and the University of California-San Francisco have found a new way to kill cancer cells, opening the ...

Sep 28, 2010
5 / 5 (8) 2 | with audio podcast