News tagged with p53 protein

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A chaperone for the 'guardian of the genome'

The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...

Sep 07, 2011
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Cancer is a p53 protein aggregation disease

Protein aggregation, generally associated with Alzheimer's and mad cow disease, turns out to play a significant role in cancer. In a paper published in Nature Chemical Biology, Frederic Rousseau and Joost Schymkowitz of VIB ...

Mar 29, 2011
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Eggs' quality control mechanism explained

To protect the health of future generations, body keeps a careful watch on its precious and limited supply of eggs. That's done through a key quality control process in oocytes (the immature eggs), which ensures elimination ...

Feb 17, 2011
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p53 determines organ size

In studies conducted on the fruit fly, researchers at IRB Barcelona (Spain) headed by ICREA Professor Marco Milan have revealed that organs have the molecular mechanisms to control their proportions. In this process the protein ...

Dec 15, 2010
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Scientists show TAp63 suppresses cancer metastasis

Long overshadowed by p53, its famous tumor-suppressing sibling, the p63 gene does the tougher, important job of stifling the spread of cancer to other organs, researchers at The University of Texas MD Anderson Cancer Center ...

Oct 20, 2010
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