News tagged with p53 mutations

Cancer is a p53 protein aggregation disease

Protein aggregation, generally associated with Alzheimer's and mad cow disease, turns out to play a significant role in cancer. In a paper published in Nature Chemical Biology, Frederic Rousseau and Joost Schymkowitz of VIB ...

Mar 29, 2011
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New function discovered in cancer prevention protein

Protein 53 is very important in protecting against cancer given that it prevents cancer-causing mutations from accumulating and its inactivation is closely linked to the proliferation of tumour cells. UAB (Universitat Autonoma ...

Jun 07, 2010
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Researchers find a weak link in cancer cell armor

(PhysOrg.com) -- Professor Robert Weiss has found that when two particular genes are inhibited, cancer cells are destroyed at a greater rate. The study is published in the Nov. 9 issue of PNAS.

Nov 11, 2009
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Tumor mutations can predict chemo success

(PhysOrg.com) -- New work by MIT cancer biologists shows that the interplay between two key genes that are often defective in tumors determines how cancer cells respond to chemotherapy.

Aug 06, 2009
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Study gives clues to how adrenal cancer forms

At the ends of chromosome are special pieces of DNA called telomeres. Think of it as the little tip that caps off a shoelace. The telomeres send signals to the cells to let them know it's the end point, not ...

Jun 04, 2009
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Newly discovered gene plays vital role in cancer

(PhysOrg.com) -- Gene p53 protects against cancer and is usually described as the most important gene in cancer research. However, scientists at the Swedish medical university Karolinska Institutet have now shown that a previously ...

Feb 27, 2009
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