News tagged with p53 mutations

Cancer is a p53 protein aggregation disease

Protein aggregation, generally associated with Alzheimer's and mad cow disease, turns out to play a significant role in cancer. In a paper published in Nature Chemical Biology, Frederic Rousseau and Joost Schymkowitz of VIB, ...

dateMar 29, 2011 in Biochemistry
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New function discovered in cancer prevention protein

Protein 53 is very important in protecting against cancer given that it prevents cancer-causing mutations from accumulating and its inactivation is closely linked to the proliferation of tumour cells. UAB (Universitat Autonoma ...

dateJun 07, 2010 in Cancer
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Tumor mutations can predict chemo success

( -- New work by MIT cancer biologists shows that the interplay between two key genes that are often defective in tumors determines how cancer cells respond to chemotherapy.

dateAug 06, 2009 in Cancer
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Study gives clues to how adrenal cancer forms

At the ends of chromosome are special pieces of DNA called telomeres. Think of it as the little tip that caps off a shoelace. The telomeres send signals to the cells to let them know it's the end point, not a break that should ...

dateJun 04, 2009 in Cancer
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