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News tagged with p53 genes

Scientists develop mouse models of leukemia that predict response to chemotherapy

Being able to accurately predict how a given cancer will respond to chemotherapy would spare patients with non-responsive tumors the burden of undergoing toxic and ultimately unhelpful treatment. Just as important, knowing ...

Medicine & Health / Cancer

created Mar 31, 2009 | popularity not rated yet | comments 1

MicroRNA undermines tumor suppression

A small piece of RNA, or microRNA (miRNA), ratchets down the activity of the tumor-suppressor gene p53, according to a study by Whitehead Institute and National University of Singapore researchers.

Biology / Cell & Microbiology

created Mar 17, 2009 | popularity not rated yet | comments 0

Regulatory molecule for tumor formation or suppression identified

One of the small regulatory molecules, named microRNA-125b, is a novel regulator of p53, an important protein that safeguards cells against cancers, Singapore and U.S. scientists report in the March 17, 2009 issue of the ...

Medicine & Health / Cancer

created Mar 17, 2009 | popularity not rated yet | comments 0

New investigational treatment for bladder cancer

A team of researchers, led by Columbia University Medical Center faculty, has identified a new investigational therapy for the treatment of bladder cancer. The discovery was made using a new research model, using mice, which ...

Medicine & Health / Cancer

created Mar 12, 2009 | popularity not rated yet | comments 0

Newly discovered gene plays vital role in cancer

(PhysOrg.com) -- Gene p53 protects against cancer and is usually described as the most important gene in cancer research. However, scientists at the Swedish medical university Karolinska Institutet have now shown that a previously ...

Medicine & Health / Cancer

created Feb 27, 2009 | popularity 4.8 / 5 (8) | comments 0

Breast cancer drug shows promise for treating, preventing progestin-dependent tumors

Recent studies suggest that human breast cancer risk is increased by outside exposure to the hormone progestin, such as during hormone replacement therapy. Now, a University of Missouri study suggests that PRIMA-1, a small ...

Medicine & Health / Cancer

created Jan 28, 2009 | popularity not rated yet | comments 0