News tagged with p53 gene

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Novel compound selectively kills cancer cells

A cancer cell may seem out of control, growing wildly and breaking all the rules of orderly cell life and death. But amid the seeming chaos there is a balance between a cancer cell's revved-up metabolism and skyrocketing ...

dateJul 13, 2011 in Biochemistry
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Researchers discover potential cancer therapy target

One of the most important genes in the human genome is called p53 and its function is to suppress tumours, according to Roger Leng, a researcher in the Faculty of Medicine & Dentistry. Leng has discovered the mechanism by ...

dateFeb 14, 2011 in Cancer
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Cancer cell survival is not 'miR-ly' dependent on p53

Squamous cell carcinoma (SCC) is a common type of skin cancer. In this paper, Leif Ellisen and colleagues at Mass General Hospital investigated the p53-related proteins p63 and p73 in SCC cells, and discovered a feedback ...

dateJan 10, 2011 in Cancer
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