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News tagged with p450

Key player in detoxification pathway isolated after decades of searching

(PhysOrg.com) -- Chemical reactions are happening all over the place all the time -- on the sun, on the Earth and in our bodies. In many cases, enzymes help make these reactions occur. One family of enzymes, ...

Chemistry / Biochemistry

created Nov 12, 2010 | popularity 5 / 5 (13) | comments 0 | with audio podcast

Supercomputer reveals new details behind drug-processing protein model

Supercomputer simulations at the Department of Energy's Oak Ridge National Laboratory are giving scientists unprecedented access to a key class of proteins involved in drug detoxification.

Chemistry / Biochemistry

created Dec 06, 2011 | popularity 4.5 / 5 (6) | comments 0 | with audio podcast

New research increases understanding of drug metabolism

Research led by Wayne L. Backes, PhD, Professor of Pharmacology and Associate Dean for Research at LSU Health Sciences Center New Orleans School of Medicine, has found that drug metabolism depends not only upon which enzymes ...

Chemistry / Biochemistry

created Mar 17, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists demystify an enzyme responsible for drug and food metabolism

Scientists led by Michael Green at Penn State University, have solved a 40-year-old puzzle about the mysterious process by which a critical enzyme metabolizes nutrients in foods and chemicals in drugs such ...

Chemistry / Biochemistry

created Nov 11, 2010 | popularity 4 / 5 (4) | comments 0 | with audio podcast

Biochemistry of how plants resist insect attack determined

Many plants, including crops, release volatiles in response to insect attack. The chemical compounds can be a defense or can be an aromatic call for help to attract enemies of the attacking insect. Researchers from Virginia ...

Biology / Plants & Animals

created Nov 15, 2010 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Genetic variation of enzyme linked with outcomes for women receiving tamoxifen

Among women with early stage breast cancer, genetic variation of a certain enzyme appears to be associated with clinical outcomes for women treated with tamoxifen, according to a study in the October 7 issue of JAMA.

Medicine & Health / Cancer

created Oct 06, 2009 | popularity not rated yet | comments 0

Caffeic acid inhibits colitis in a mouse model -- is a drug-metabolizing gene crucial?

Researchers at Iowa State University have found that increased expression of a form of cytochrome P-450 (CYP4B1) is a key marker of inhibition of colitis in mice by caffeic acid, an anti-inflammatory antioxidant compound ...

Medicine & Health / Medical research

created May 26, 2009 | popularity 3 / 5 (1) | comments 0