News tagged with overexpression

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Greater accuracy in gauging blood coagulation

Thrombin plays a key role in various pathologies of the haemostatic system. Overexpression of thrombin can result in thrombosis, whereas its underexpression might lead to haemophilia. Therefore, accurate monitoring ...

dateFeb 23, 2012 in Biochemistry
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Different signaling pathways of cholangiocarcinoma

Overexpression of receptor tyrosine kinase Met has frequently been found in cholangiocarcinoma. A research group in Thailand demonstrated that hepatocyte growth factor, a Met ligand, induced invasion and motility and altered ...

dateMar 04, 2010 in Cancer
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New subtype of breast cancer responds to targeted drug

A newly identified cancer biomarker could define a new subtype of breast cancer as well as offer a potential way to treat it, say researchers at Washington University School of Medicine in St. Louis. Their findings will be ...

dateMar 01, 2010 in Cancer
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New prognostic marker for human breast cancer

Elevated levels of GLI1 (glioma-associated oncogene homolog 1) protein in human breast cancer are associated with unfavorable prognosis and progressive stages of disease. Researchers writing in the open access journal BMC Ca ...

dateAug 24, 2009 in Cancer
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