News tagged with overexpression

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Greater accuracy in gauging blood coagulation

Thrombin plays a key role in various pathologies of the haemostatic system. Overexpression of thrombin can result in thrombosis, whereas its underexpression might lead to haemophilia. Therefore, accurate monitoring ...

Feb 23, 2012
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Different signaling pathways of cholangiocarcinoma

Overexpression of receptor tyrosine kinase Met has frequently been found in cholangiocarcinoma. A research group in Thailand demonstrated that hepatocyte growth factor, a Met ligand, induced invasion and motility and altered ...

Mar 04, 2010
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New subtype of breast cancer responds to targeted drug

A newly identified cancer biomarker could define a new subtype of breast cancer as well as offer a potential way to treat it, say researchers at Washington University School of Medicine in St. Louis. Their findings will be ...

Mar 01, 2010
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New prognostic marker for human breast cancer

Elevated levels of GLI1 (glioma-associated oncogene homolog 1) protein in human breast cancer are associated with unfavorable prognosis and progressive stages of disease. Researchers writing in the open access journal BMC Ca ...

Aug 24, 2009
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MEK4, genistein and invasion of human prostate cancer cells

Researchers have identified MEK4 as a pro-invasion protein and the target for genistein, a dietary compound, in prostate cancer cells, according to a new study published online July 28 in the Journal of the National Cancer In ...

Jul 28, 2009
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