Considered the most lethal form of DNA damage, double-strand breaks must be repaired to prevent cell death. In developing therapies for hard-to-treat breast and ovarian cancers in patients with BRCA gene mutations, scientists ...
Cell & Microbiology
Feb 11, 2021
0
271
PARP inhibitors are recently developed drugs that have shown great promise against some types of ovarian, breast, prostate and pancreatic cancer, but many patients' tumors develop resistance to the drugs. Now researchers ...
Cell & Microbiology
Jan 19, 2021
0
24
Maybe you go for a leisurely walk, curl up with a good book, lift weights or reach for some comfort food when you're not feeling well or have had a particularly stressful day. Although there are myriad ways that we all outwardly ...
Plants & Animals
Nov 18, 2020
0
40
While scientists know of about 25,000 genes that code for biologically important proteins, additional, smaller genes hiding in our DNA may be just as important. But these tiny lines of genetic code have proven tough to track ...
Biotechnology
Dec 9, 2019
0
14
Researchers at Oregon State University have developed an improved technique for using magnetic nanoclusters to kill hard-to-reach tumors.
Bio & Medicine
Jun 27, 2019
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3
Identifying a protein that plays a key role in cancer cell growth is a first step toward the development of a targeted cancer therapy. It is especially promising when this protein is dispensable for the growth of normal cells. ...
Biochemistry
Apr 19, 2019
0
129
Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now, in a new paper published in Nature Structural & Molecular Biology, Mayo researchers have determined how one DNA repair protein gets ...
Cell & Microbiology
Jul 2, 2018
0
39
A new anticancer agent developed by the University of Warwick has been studied using microfocus synchrotron X-ray fluorescence (SXRF) at I18 at Diamond Light Source. As described in the Journal of Inorganic Biochemistry, ...
Biochemistry
Jun 19, 2018
0
28
Researchers at Rice University and the University of Texas MD Anderson Cancer Center have refined and, for the first time, run in vivo tests of a method that may allow nanotube-based probes to locate specific tumors in the ...
Nanophysics
Nov 30, 2017
0
264
A drug used now to treat Type 2 diabetes may someday help beat breast and ovarian cancers, but not until researchers decode the complex interactions that in some cases help promote tumors, according to Rice University scientists.
Biochemistry
Nov 30, 2016
0
220
