Bone may seem as if it's a hard, lifeless structure, but now the cells living within have been imaged in unprecedented detail, thanks to an innovative imaging method developed at the Garvan Institute of Medical Research.
Cell & Microbiology
Oct 26, 2023
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once believed to bear fruit that ripened into a living baby sheep — produces substances that show promise in laboratory experiments as new treatments for osteoporosis, the bone-thinning disease. That's the conclusion of ...
Biochemistry
Oct 14, 2009
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In today's aging societies, bone and joint diseases are becoming increasingly common. For example, in Japan alone, over 12 million people suffer from osteoporosis, a condition that severely weakens bones and makes them fragile. ...
Cell & Microbiology
Feb 6, 2024
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Bone is maintained via a delicate balance between formation and resorption, and its imbalance leads to bone related diseases like osteoporosis, rheumatism and periodontitis.
Cell & Microbiology
Oct 26, 2023
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Bones remain healthy thanks to the fact that they are continuously remodeling, a process dependent on the balance between the activity of osteoblasts—cells that create bone tissue—and the osteoclasts, which reabsorb it. ...
Cell & Microbiology
Mar 3, 2023
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Researchers in Hong Kong are reporting new evidence that green tea — one of the most popular beverages consumed worldwide and now available as a dietary supplement — may help improve bone health. They found that the tea ...
Biochemistry
Sep 16, 2009
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An osteoclast (from the Greek words for "bone" (Οστό) and "broken" (κλαστός)) is a type of bone cell that removes bone tissue by removing its mineralized matrix and breaking up the organic bone (organic dry weight is 90% collagen). This process is known as bone resorption. Osteoclasts were discovered by Kolliker in 1873. Osteoclasts and osteoblasts are instrumental in controlling the amount of bone tissue: osteoblasts form bone, osteoclasts resorb bone. Osteoclasts are formed by the fusion of cells of the monocyte-macrophage cell line. Osteoclasts are characterized by high expression of tartrate resistant acid phosphatase (TRAP) and cathepsin K.
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