News tagged with osteoclasts

Osteoclast

An osteoclast (from the Greek words for "bone" (Οστό) and "broken" (κλαστός)) is a type of bone cell that removes bone tissue by removing its mineralized matrix and breaking up the organic bone (organic dry weight is 90% collagen). This process is known as bone resorption. Osteoclasts were discovered by Kolliker in 1873. Osteoclasts and osteoblasts are instrumental in controlling the amount of bone tissue: osteoblasts form bone, osteoclasts resorb bone. Osteoclasts are formed by the fusion of cells of the monocyte-macrophage cell line. Osteoclasts are characterized by high expression of tartrate resistant acid phosphatase (TRAP) and cathepsin K.

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Exercise can forestall osteoporosis

The stage for osteoporosis is set well before menopause—but exercise can help rewrite the script, according to Medical College of Georgia researchers.

Medicine & Health / Diseases, Conditions, Syndromes

created Apr 26, 2010 | popularity 5 / 5 (1) | comments 0

Fabled 'vegetable lamb' plant contains potential treatment for osteoporosis

once believed to bear fruit that ripened into a living baby sheep — produces substances that show promise in laboratory experiments as new treatments for osteoporosis, the bone-thinning disease. That's the conclusion of a ...

Chemistry / Biochemistry

created Oct 14, 2009 | popularity 4.3 / 5 (7) | comments 1

New evidence that green tea may help improve bone health

Researchers in Hong Kong are reporting new evidence that green tea — one of the most popular beverages consumed worldwide and now available as a dietary supplement — may help improve bone health. They found ...

Chemistry / Biochemistry

created Sep 16, 2009 | popularity 5 / 5 (1) | comments 0

New function for the protein Bcl-xL: It prevents bone breakdown

In blood cells, the protein Bcl-xL has a well-characterized role in preventing cell death by a process known as apoptosis. However, its function(s) in osteoclasts, cells that slowly breakdown bone (a process known as resorption), ...

Medicine & Health / Medical research

created Sep 14, 2009 | popularity 5 / 5 (1) | comments 0