News tagged with oncogenes
Jarid2 may break the Polycomb silence
Historically, fly and human Polycomb proteins were considered textbook exemplars of transcriptional repressors, or proteins that silence the process by which DNA gives rise to new proteins. Now, work by a ...
Apr 30, 2012 |
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Gene may be good target for tough-to-kill prostate cancer cells
Purdue University scientists believe they have found an effective target for killing late-stage, metastatic prostate cancer cells.
Sep 27, 2011 |
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Worm studies shed light on human cancers
(PhysOrg.com) -- Research in the worm is shedding light on a protein associated with a number of different human cancers, and may point to a highly targeted way to treat them.
Apr 21, 2011 |
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Protein found to be the link missing between HPV infection and cervical cancer development
Most women are infected with human papillomavirus (HPV), which can cause cervical cancer - yet few develop the cancer. Now researchers at Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University Medical ...
Apr 05, 2011 |
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Nicotine does not promote lung cancer growth in mouse models
Nicotine at doses similar to those found in most nicotine replacements therapies did not increase lung cancer tumor incidence, frequency or size, according to results of a mouse study presented at the AACR 102nd Annual Meeting ...
Apr 04, 2011 |
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Scientists identify KRAS rearrangements in metastatic prostate cancer
Scientists have uncovered a genetic characteristic of metastatic prostate cancer that defines a rare sub-type of this disease. These findings are published in Cancer Discovery, the newest journal of the American Association for Ca ...
Apr 03, 2011 |
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UT Southwestern research advances fight against kidney cancer
Researchers at UT Southwestern Medical Center have discovered genetic pathways to starve selectively kidney cancer cells.
Mar 30, 2011 |
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Study identifies therapeutic target for liver cancer and predictive biomarker of response
In a research study appearing in the journal Cancer Cell on March 14, scientists from Cold Spring Harbor Laboratory (CSHL) and four other institutions have identified a strategy for targeted molecular therapy in liver cancer ...
Mar 14, 2011 |
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Scientists discover first breast cancer 'oncogene' in five years
(PhysOrg.com) -- Scientists have pinpointed a key cancer-causing gene that, when overactive, triggers a particularly aggressive type of breast cancer to develop.
Feb 18, 2011 |
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Study unmasks a stem cell origin of skin cancer and the genetic roots of malignancy
A constellation of different stem cell populations within our skin help it to cope with normal wear and tear. By constantly proliferating, the stem cells allow skin to replenish itself, allowing each cell to be replaced by ...
Feb 03, 2011 |
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Roundworm unlocks pancreatic cancer pathway
The National Cancer Institute estimates that more than 43,000 Americans were diagnosed with pancreatic cancer last year and more than 36,000 died from the disease. Despite advances in genetic science showing that the Ras ...
Jan 19, 2011 |
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Researchers make major breakthrough in melanoma research
In a breakthrough that could lead to new treatments for patients with malignant melanoma, researchers from Mount Sinai School of Medicine have discovered that a particular protein suppresses the progression of melanoma through ...
Dec 22, 2010 |
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Breast inflammation is key to cancer growth, researchers say
It took 12 years and a creation of a highly sophisticated transgenic mouse, but researchers at Kimmel Cancer Center at Jefferson have finally proven a long suspected theory: Inflammation in the breast is key to the development ...
Dec 15, 2010 |
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New gene for childhood cancer neuroblastoma discovered
Pediatric cancer researchers have identified variations in a gene as important contributors to neuroblastoma, the most common solid cancer of early childhood. The study team, led by researchers at The Children's Hospital ...
Dec 01, 2010 |
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Novel genetic mutation that causes the most common form of eye cancer discovered
An international, multi-center study has revealed the discovery of a novel oncogene that is associated with uveal melanoma, the most common form of eye cancer. Researchers have isolated an oncogene called GNA11 and have found ...
Nov 17, 2010 |
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Oncogene
An oncogene is a gene that has the potential to cause cancer. In tumor cells, they are often mutated or expressed at high levels. An oncogene is a gene found in the chromosomes of tumor cells whose activation is associated with the initial and continuing conversion of normal cells into cancer cells.
Most normal cells undergo a programmed form of death (apoptosis). Activated oncogenes can cause those cells that ought to die to survive and proliferate instead. Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer. Since the 1970s, dozens of oncogenes have been identified in human cancer. Many cancer drugs target the proteins encoded by oncogenes.
For more information about Oncogene, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
