Deciphering potent DNA toxin's secrets

One of the most potent toxins known acts by welding the two strands of the famous double helix together in a unique fashion which foils the standard repair mechanisms cells use to protect their DNA.

Storing data in DNA brings nature into the digital universe

Humanity is producing data at an unimaginable rate, to the point that storage technologies can't keep up. Every five years, the amount of data we're producing increases 10-fold, including photos and videos. Not all of it ...

How RNA formed at the origins of life

A single process for how a group of molecules called nucleotides were made on the early Earth, before life began, has been suggested by a UCL-led team of researchers.

Oddball enzyme provides easy path to synthetic biomaterials

Materials scientists have written the recipe on how to use an oddball enzyme to build new biomaterials out of DNA. The work provides instructions for researchers the world over to build self-assembling molecules for applications ...

Mechanism for hMTH1's broad substrate specificity revealed

Human MutT homolog 1 (hMTH1) protein acts as the primary enzyme for breaking down (hydrolyzing) damaged (oxidized) deoxynucleoside triphosphates (dNTPs) the substrates of DNA synthesis. Recently, hMTH1 has drawn attention ...

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