Evolving strains of multi-drug resistant pathogens are a growing global concern, outpacing drug discovery efforts and undermining the efficacy of existing antibiotics. The development of comprehensive diagnostics for clinical ...
When trying to understand the origins of life on Earth, researchers run into a paradox: while water is an indispensable solvent for all known life forms that exist today, water also inhibits the formation of string-like chains ...
Handedness is a complicated business. To simply say life is left-handed doesn't even begin to capture the blooming hierarchy of binary refinements it continues to evolve. Over the years there have been numerous imaginative ...
If there is life in the solar system beyond Earth, it might be found in the clouds of Venus. In contrast to the planet's blisteringly inhospitable surface, Venus' cloud layer, which extends from 30 to 40 miles above the surface, ...
Astrobiology
Mar 20, 2024
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204
By attaching molecules together, scientists at Université de Montréal think they've found how molecular systems at the origin of life evolved to create complex self-regulating functions.
Bio & Medicine
Feb 7, 2024
1
232
Research led by the University of Pennsylvania, Philadelphia, has used siRNA-based silencing of protein cyclophilin A (CyPA) to reduce tumor burden and extend the lives of patients with multiple myeloma.
Mammalian cells are inherently complex due to subcellular compartments, thereby making the process of robust transcript targeting of nucleic acids somewhat challenging in the molecular biology lab. In a recent report now ...
"Every act of creation," Picasso famously noted, "is first an act of destruction."
Bio & Medicine
Feb 9, 2023
1
124
Four billion years ago, the Earth looked very different than it does today, devoid of life and covered by a vast ocean. Over the course of millions of years, in that primordial soup, life emerged. Researchers have long theorized ...
Biochemistry
Jul 28, 2022
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2232
According to a new concept by LMU chemists led by Thomas Carell, it was a novel molecular species composed out of RNA and peptides that set in motion the evolution of life into more complex forms.
Evolution
May 12, 2022
2
1050
A nucleic acid is a macromolecule composed of chains of monomeric nucleotides. In biochemistry these molecules carry genetic information or form structures within cells. The most common nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Nucleic acids are universal in living things, as they are found in all cells and viruses. Nucleic acids were first discovered by Friedrich Miescher in 1871.
Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally-occurring DNA or RNA by changes to the backbone of the molecule.
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